Chitosan-based hydrogels prepared by UV polymerization for wound dressing

Yao, Han; Lin, Hong; Sue, Geng Pin; Lin, Yiu Jiuan

doi:10.1177/0967391118820477

Cited by 15 publications

(8 citation statements)

References 32 publications

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“…Yao et al [39] prepared CS-based hydrogels by grafting poly(acrylic acid) and poly(hydroxyethyl methacrylate), and the epidermal growth factor (EGF) was incorporated to stimulate the wound healing effect. The physical characterization of hydrogels depicted their high hydrophilicity with adequate wound dressing properties.…”

Section: Biomaterials For Wound Managementmentioning

confidence: 99%

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Okur

Karantas

Şenyiğit

et al. 2020

Asian Journal of Pharmaceutical Sciences

204

115

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Wound healing is an unmet therapeutic challenge among medical society since wound assessment and management is a complex procedure including several factors playing major role in healing process. Wounds can mainly be categorized as acute or chronic. It is well referred that the acute wound displays normal wound physiology while healing, in most cases, is seemed to progress through the normal phases of wound healing. On the other hand, a chronic wound is physiologically impaired. The main problem in wound management is that the majority of wounds are colonized with microbes, whereas this does not mean that all wounds will be infected. In this review, we address the problems that clinicians face to manage while treat acute and chronic wounds. Moreover, we demonstrate the pathophysiology, etiology, prognosis and microbiology of wounds. We further introduce the state of art in pharmaceutical technology field as part of wound management aiming to assist health professionals to overcome the current implications on wound assessment. In addition, authors review researches which included the use of gels and dermal films as wound healing agents. It can be said that natural and synthetic drugs or carriers provide promising solutions in order to meet the wound management standards. However, are the current strategies as desirable as medical society wish?

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Section: Biomaterials For Wound Managementmentioning

confidence: 99%

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Okur

Karantas

Şenyiğit

et al. 2020

Asian Journal of Pharmaceutical Sciences

204

115

View full text Add to dashboard Cite

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“…Chitosan hydrogels have weak mechanical strength, limiting their application as biomimetic materials. To improve the mechanical properties, chemical crosslinking [93,202,203], blending with other polymers [204,205], or nanofillers reinforcement [42] Compared to natural soft tissues (cartilage or ligament), the mechanical strength in CSbased hydrogels remains weak. Using these approaches for building networks, unordered structure and moderate enhancement of mechanical properties are obtained, whereas the inherent beneficial properties of CS included into the hydrogels remain detrimental.…”

Section: Chitosan and Chitinmentioning

confidence: 99%

Bioinspired Hydrogels as Platforms for Life-Science Applications: Challenges and Opportunities

Bercea¹

2022

Polymers

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Hydrogels, as interconnected networks (polymer mesh; physically, chemically, or dynamic crosslinked networks) incorporating a high amount of water, present structural characteristics similar to soft natural tissue. They enable the diffusion of different molecules (ions, drugs, and grow factors) and have the ability to take over the action of external factors. Their nature provides a wide variety of raw materials and inspiration for functional soft matter obtained by complex mechanisms and hierarchical self-assembly. Over the last decade, many studies focused on developing innovative and high-performance materials, with new or improved functions, by mimicking biological structures at different length scales. Hydrogels with natural or synthetic origin can be engineered as bulk materials, micro- or nanoparticles, patches, membranes, supramolecular pathways, bio-inks, etc. The specific features of hydrogels make them suitable for a wide variety of applications, including tissue engineering scaffolds (repair/regeneration), wound healing, drug delivery carriers, bio-inks, soft robotics, sensors, actuators, catalysis, food safety, and hygiene products. This review is focused on recent advances in the field of bioinspired hydrogels that can serve as platforms for life-science applications. A brief outlook on the actual trends and future directions is also presented.

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“…Hydrogels present multiple advantages for wound dressings, such as oxygenation, water permeability, the preservation of a moist microenvironment, etc. [ 79 , 80 , 81 , 82 , 83 ]. Inorganic nanomaterials such as metals [ 84 ], transition metals [ 85 ], and carbon-based nanomaterials [ 86 ] with a photothermal effect can be incorporated into hydrogels to improve the photothermal capacities.…”

Section: Polymer-based Nanomaterialsmentioning

confidence: 99%

Nanomaterials for the Photothermal Killing of Bacteria

et al. 2020

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An upsurge in the multidrug-resistant (MDR) bacterial pestilence is a global cause for concern in terms of human health. Lately, nanomaterials with photothermal effects have assisted in the efficient killing of MDR bacteria, attributable to their uncommon plasmonic, photocatalytic, and structural properties. Examinations of substantial amounts of photothermally enabled nanomaterials have shown bactericidal effects in an optimized time under near-infrared (NIR) light irradiation. In this review, we have compiled recent advances in photothermally enabled nanomaterials for antibacterial activities and their mechanisms. Photothermally enabled nanomaterials are classified into three groups, including metal-, carbon-, and polymer-based nanomaterials. Based on substantial accomplishments with photothermally enabled nanomaterials, we have inferred current trends and their prospective clinical applications.

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Chitosan-based hydrogels prepared by UV polymerization for wound dressing

Cited by 15 publications

References 32 publications

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Bioinspired Hydrogels as Platforms for Life-Science Applications: Challenges and Opportunities

Nanomaterials for the Photothermal Killing of Bacteria

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