Chitin and derivative chitosan-based structures — Preparation strategies aided by deep eutectic solvents: A review

Khajavian, Mohammad; Vatanpour, Vahid; Castro‐Muñoz, Roberto; Boczkaj, Grzegorz

doi:10.1016/j.carbpol.2021.118702

Cited by 160 publications

(73 citation statements)

References 96 publications

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“…The molar percentage of N-acetylated units distinguishes chitin from chitosan and is used to calculate the deacetylation degree (DDA), which indicates the balance between the two kinds of residues. The product is called chitosan when the DDA amount is greater than 50% [50]. Acetyl groups are removed during deacetylation, where depolymerization also occurs resulting in variations in chitosan molecular weight (Mw) [50].…”

Section: Chitosanmentioning

confidence: 99%

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Electrospinning of Chitosan for Antibacterial Applications—Current Trends

2021

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Chitosan is a natural biopolymer that can be suitable for a wide range of applications due to its biocompatibility, rigid structure, and biodegradability. Moreover, it has been proven to have an antibacterial effect against several bacteria strains by incorporating the advantages of the electrospinning technique, with which tailored nanofibrous scaffolds can be produced. A literature search is conducted in this review regarding the antibacterial effectiveness of chitosan-based nanofibers in the filtration, biomedicine, and food protection industries. The results are promising in terms of research into sustainable materials. This review focuses on the electrospinning of chitosan for antibacterial applications and shows current trends in this field. In addition, various aspects such as the parameters affecting the antibacterial properties of chitosan are presented, and the application areas of electrospun chitosan nanofibers in the fields of air and water filtration, food storage, wound treatment, and tissue engineering are discussed in more detail.

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Section: Chitosanmentioning

confidence: 99%

“…The product is called chitosan when the DDA amount is greater than 50% [50]. Acetyl groups are removed during deacetylation, where depolymerization also occurs resulting in variations in chitosan molecular weight (Mw) [50].…”

Section: Chitosanmentioning

confidence: 99%

Electrospinning of Chitosan for Antibacterial Applications—Current Trends

2021

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“…FT-IR spectrum of Trichoderma asperellum chitosan was not different with commercial chitosan. Some prominent band 1661 cm −1 1559 cm −1 1315 cm −1 corresponded to the stretching vibration of C=O (amide band I), N-H (amide band II) and N-H (amide band II), and the signal near at 1118 cm −1 and 1072 cm −1 were due to C-O-C and C-O stretching, which were characteristic band of chitosan (Khajavian et al, 2022). Besides the absorption peak at near 3356 cm −1 was attributed to the stretching vibration of -OH.…”

Section: Ftir Spectrum Analysismentioning

confidence: 99%

“…. MICs of COS-1 against E. coli, S. aureus, B. subtilis and S. bacilli were 15.80, 15.57,15.72 and 6.87 mg/mL, respectively. And the corresponding MICs of COS-2 were 15.93, 15.93, 15.80 and 15.90 mg/mL, respectively.…”

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confidence: 95%

Trichoderma Asperellum as a Novel Source to Prepare Chitosan Oligosaccharides by Enzymatic Hydrolysis and Its Antimicrobial Activity

Wang

Zhang

Pan

et al. 2022

Preprint

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Chitosan oligosaccharides (COS), as an important biological functional component, are mainly produced from marine resources, while their source face great challenges, such as seasonal variation, discontinuity and demineralization. In this study, the chitosan was extracted by alkaline method from Trichoderma asperellum, and then it was degraded with enzymatic hydrolysis to obtain the COS. The physicochemical characterization of chitosan from Trichoderma asperellum was compared with commercial chitosan, including chitosan content, deacetylation degree, chemical group, and molecular weight. Then, the enzymatic hydrolysis rates of Trichoderma asperellum chitosan and commercial chitosan were similar, 89.37 and 91.56%, respectively. Moreover, the composition of COS was tested by TLC, HPLC and MALDI-TOF, which results shown that Trichoderma asperellum COS was composed of chitotriose, chitopentaose and chitohexaose, and commercial COS was composed of chitotriose, chitotetraose, chitopentaose, chitohexaose and four acetylated chitohexaose. The antibacterial activity for Trichoderma asperellum COS was greatly stronger commercial COS. In conclusion, Trichoderma asperellum proved to be a novel potential source for COS production.

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“…Chitosan is a biopolymer containing glucosamine, N-acetylglucosamine, and distilled alkaline products of chitin. This compound has non-toxic, biological, and biodegradable properties, with low cost (9,10). Considerable research has been undertaken to improve the properties of chitosan for medicinal uses.…”

mentioning

confidence: 99%

Novel Wound Dressing Based on Postbiotic/Chitosan Film Accelerates Cutaneous Wound Healing

Jamaran

Jafari

Marjani

et al. 2022

Jundishapur J Microbiol

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Background: Wound healing is a complex and overlapping process involving immune cells, cytokines, and growth factors. Objectives: This study aimed to design and evaluate a novel wound dressing based on postbiotic/chitosan in accelerating wound healing. Methods: Lactobacillus reuteri PTCC1655 was cultured, and the cell-free supernatant (postbiotic) was obtained by medium centrifugation. The films were prepared using the solvent casting method and evaluated in terms of water absorption index, water vapor transmission rate, and antimicrobial properties. Forty-five male Wistar rats were subjected to a full-thickness excisional wound to assess the wound healing potential. The rats were randomly divided into ctrl-, chitosan, and postbiotic groups. The time-course histological and gene expression analysis was performed to compare the dressing efficacy. Results: The films showed proper water absorption and water vapor transmission rate and inhibited the pathogens commonly associated with wound infection. The postbiotic film improved wound healing by modulating the inflammatory phase, increasing collagen and elastin deposition, and enhancing angiogenesis based on the histological results. The gene expression assay showed that the postbiotic film accelerated wound healing by improving the expression of inflammatory mediators (IL-6 and TNF-α) and anti-inflammatory mediators (TGF-β and VEGF). Conclusions: The cell-free supernatant/chitosan/polyethylene glycol (CFS/CS/PEG) biodegradable film could be introduced as a novel dressing for cutaneous wound healing. This transparent film enhances cutaneous wound healing by modulating infiltrated immunity cells and expressing inflammatory/anti-inflammatory cytokines.

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Chitin and derivative chitosan-based structures — Preparation strategies aided by deep eutectic solvents: A review

Cited by 160 publications

References 96 publications

Electrospinning of Chitosan for Antibacterial Applications—Current Trends

Electrospinning of Chitosan for Antibacterial Applications—Current Trends

Trichoderma Asperellum as a Novel Source to Prepare Chitosan Oligosaccharides by Enzymatic Hydrolysis and Its Antimicrobial Activity

Novel Wound Dressing Based on Postbiotic/Chitosan Film Accelerates Cutaneous Wound Healing

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