Chirality from substitution: enantiomer separation via a modified metal–organic framework

Abstract

A microporous MOF structure, d-his–ZIF-8, with a chiral environment was synthesized via ligand in situ substitution (LIS), which shows exceptional selective separation capability for racemic amino acids.

Protein‐Structure‐Directed Metal–Organic Zeolite‐like Networks as Biomacromolecule Carriers

“…We attribute these observations to histidine being an α‐amino acid with an imidazole functional group. Indeed, histidine has already been incorporated into the sod network of ZIF‐8 as a co‐ligand due to its similar coordination geometry to 2‐methyl imidazole . We found that 2‐methyl imidazole can also template the formation of ZPF‐1 , once again indicative of the key role of imidazole moieties in the templating process (Supporting Information, Figure S14).…”

Protein‐Structure‐Directed Metal–Organic Zeolite‐like Networks as Biomacromolecule Carriers

“…Indeed, histidine has already been incorporated into the sod network of ZIF-8 as a co-ligand due to its similar coordination geometry to 2-methyl imidazole. [31,32] We found that 2-methyl imidazole can also template the formation of ZPF-1, once again indicative of the key role of imidazole moieties in the templating process (Supporting Information, Figure S14). Thus, it is reasonable to assert that the imidazole moieties in histidine can form structural precursors of the sod network in the initial reaction stage and thereafter be substituted by excess pyrimidin-2-ol in the following step to generate the observed sod network (Scheme 2).…”

Enhanced Circularly Polarized Luminescence from Reorganized Chiral Emitters on the Skeleton of a Zeolitic Imidazolate Framework

“…Extensive studies about ZIFs have been reported because of their potential applications in gas separation, storage,s ensing,a nd other things. [13] In this work, we report the design of apair of chiral emitters based on abinaphthyldiamine moiety with 4-(10-phenylanthrancen-9-yl)phenyl and functional imi-dazole groups (R-/S-1, Figure 1), which were found to emit circularly polarized light with asmall j g lum j value of 7.0 10 À4 in dilute solution. [13] In this work, we report the design of apair of chiral emitters based on abinaphthyldiamine moiety with 4-(10-phenylanthrancen-9-yl)phenyl and functional imi-dazole groups (R-/S-1, Figure 1), which were found to emit circularly polarized light with asmall j g lum j value of 7.0 10 À4 in dilute solution.…”

“…[12] However, very few chiral ZIFs have been developed due to the tedious synthesis of enantiopure ligands and their weak coordination and crystallization. [13] In this work, we report the design of apair of chiral emitters based on abinaphthyldiamine moiety with 4-(10-phenylanthrancen-9-yl)phenyl and functional imi- dazole groups (R-/S-1, Figure 1), which were found to emit circularly polarized light with asmall j g lum j value of 7.0 10 À4 in dilute solution. After blending with one kind of Zn-based ZIF (ZIF-8) nanoparticles,aligand exchange between the chiral emitters and 2-methylimidazole (Hmim) occurred, which resulted in uniform emissive ZIF nanoparticles (R-/S-ZIF).…”