Chiral Resolution using Supramolecular‐Templated Mesostructured Materials

Huang, Yanan; Vidal, Xavier; Garcia‐Bennett, Alfonso E.

doi:10.1002/anie.201900950

Cited by 20 publications

(13 citation statements)

References 23 publications

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“…[1][2][3][4][5][6] Over the last decade,chiral nanoparticles (NPs) have been widely used in chiral catalysis,e nantiospecific separation, chiral sensing,o ptical devices,a nd many other applications. [7][8][9][10][11][12][13][14] More recently,c hiral metal nanomaterials prepared with chiral amino acids or peptides have attracted significant attention due to their intense optical activities and good biocompatibility. [15][16][17][18][19] Chiral NPs can also be subjected to various surface modifications and display tunable absorbance.T hese properties extend the applicability of chiral NPs in chiroptical fields.…”

Section: Introductionmentioning

confidence: 99%

“…Because of their specific photochemical properties, chiral nanomaterials have become increasingly popular objects of research . Over the last decade, chiral nanoparticles (NPs) have been widely used in chiral catalysis, enantiospecific separation, chiral sensing, optical devices, and many other applications . More recently, chiral metal nanomaterials prepared with chiral amino acids or peptides have attracted significant attention due to their intense optical activities and good biocompatibility .…”

Section: Introductionmentioning

confidence: 99%

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Light‐Induced Chiral Iron Copper Selenide Nanoparticles Prevent β‐Amyloidopathy In Vivo

et al. 2020

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The accumulation and deposition of β‐amyloid (Aβ) plaques in the brain is considered a potential pathogenic mechanism underlying Alzheimer's disease (AD). Chiral l/d‐FexCuySe nanoparticles (NPs) were fabricated that interfer with the self‐assembly of Aβ42 monomers and trigger the Aβ42 fibrils in dense structures to become looser monomers under 808 nm near‐infrared (NIR) illumination. d‐FexCuySe NPs have a much higher affinity for Aβ42 fibrils than l‐FexCuySe NPs and chiral Cu2−xSe NPs. The chiral FexCuySe NPs also generate more reactive oxygen species (ROS) than chiral Cu2−xSe NPs under NIR‐light irradiation. In living MN9D cells, d‐NPs attenuate the adhesion of Aβ42 to membranes and neuron loss after NIR treatment within 10 min without the photothermal effect. In‐vivo experiments showed that d‐FexCuySe NPs provide an efficient protection against neuronal damage induced by the deposition of Aβ42 and alleviate symptoms in a mouse model of AD, leading to the recovery of cognitive competence.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Light‐Induced Chiral Iron Copper Selenide Nanoparticles Prevent β‐Amyloidopathy In Vivo

et al. 2020

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“…The imprinting chirality of CMS can also make it work in stereoselective adsorption of l - and d -phenylalanine with a chiral selective factor of 3.24 [ 49 ]. The chiral transcription of guanosine monophosphate and folic acid onto mesoporous silica is disclosed via the kinetic adsorption of enantiomeric pairs including d -(−)-Tartaric acid and l -(+)-Tartaric acid, l -Valine, and d -Valine, as well as (+)-a-Pinene and (−)-a-Pinene [ 80 ]. The two samples exhibited opposite enantiomeric selectivity for enantiomeric pairs due to the chiral transcription process.…”

Section: Applications Of Chiral Mesoporous Silicamentioning

confidence: 99%

Chiral Mesoporous Silica Materials: A Review on Synthetic Strategies and Applications

et al. 2020

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Because of its tunable textural properties and chirality feature, chiral mesoporous silica (CMS) gained significant consideration in many fields and has been developed rapidly in recent years. In this review, we provide an overview of synthesis strategies for fabricating CMS together with its main applications. The properties of CMS, including morphology and mesostructures and enantiomer excess (ee), can be altered according to the synthetic conditions during the synthesis process. Despite its primary stage, CMS has attracted extensive attention in many fields. In particular, CMS nanoparticles are widely used for enantioselective resolution and adsorption of chiral compounds with desirable separation capability. Also, CMS acts as a promising candidate for the effective delivery of chiral or achiral drugs to produce a chiral-responsive manner. Moreover, CMS also plays an important role in chromatographic separations and asymmetric catalysis. There has been an in-depth review of the synthetic methods and mechanisms of CMS. And this review aims to give a deep insight into the synthesis and application of CMS, especially in recent years, and highlights the significance that it may have in the future.

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“…The additional organic functionalization offers chirality on the surface of the mesopores, which are effectively used for the separation of enantiomeric pairs. This provides a fantastic opportunity for the enantiomeric catalysis …”

Section: Synthesis Of Organo‐functionalized Molecular Sievesmentioning

confidence: 99%

Recent Advances in the Preparation and Applications of Organo‐functionalized Porous Materials

Yadav

Baskaran

Anjali

et al. 2020

Chemistry An Asian Journal

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Organo‐functionalized materials with porous structure offer unique adsorption, catalytic and sensing properties. These unique properties make them available for various applications, including catalysis, CO2 capture and utilization, and drug delivery. The properties and the performance of these unique materials can be altered with suitable modifications on their surface. In this review, we summarize the recent advances in the preparation and applications of organo‐functionalized porous materials with different structures. Initially, a brief historical overview of functionalized porous materials is presented, and the subsequent sections discuss the recent developments and applications of various functional porous materials. In particular, the focus is given on the various methods used for the preparation of organo‐functionalized materials and their important roles in the heterogenization of homogeneous catalysts. A special emphasis is also given on the applications of these functionalized porous materials for catalysis, CO2 capture and drug delivery.

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Chiral Resolution using Supramolecular‐Templated Mesostructured Materials

Cited by 20 publications

References 23 publications

Light‐Induced Chiral Iron Copper Selenide Nanoparticles Prevent β‐Amyloidopathy In Vivo

Light‐Induced Chiral Iron Copper Selenide Nanoparticles Prevent β‐Amyloidopathy In Vivo

Chiral Mesoporous Silica Materials: A Review on Synthetic Strategies and Applications

Recent Advances in the Preparation and Applications of Organo‐functionalized Porous Materials

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