Chiral quaternary ammonium ionic liquids derived from natural dehydroabietylamine and their potential application in chiral molecular recognition

Yan, Jingjing; Zhu, Yi; Hu, Gang; Liang, Qinghui; Ge, Li; Yang, Kang

doi:10.1016/j.tet.2022.133165

Cited by 2 publications

(3 citation statements)

References 43 publications

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“…Selection and modification of the anion and cation of the quaternary ammonium-based ILs with positive nitrogen could form tune physical properties, such as good melting, water-solubility, rate of conduction, and viscosity ( 12 ). Antimicrobial activity of the alkyl group on the different infective agents has been previously shown ( 13 , 14 ). ILs can dissolve organic components, especially DNA molecules.…”

Section: Introductionmentioning

confidence: 94%

Effect of new methionine-based ionic liquid on the CDR1 and CDR2 gene expression on sensitive and resistant strains of Candida albicans

Eslami

Ezabadi

Bayat

et al. 2023

IJM

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Background and Objectives: Previous researchers showed the antimicrobial ability of ionic liquids (ILs) on different infec- tive agents. ILs can dissolve organic components, especially DNA molecules. Among synthesized eight binary ILs mixtures, we have chosen ([Met-HCl] [PyS]) IL for determining the antifungal ability of IL against Candida albicans cells. Materials and Methods: Well diffusion assay, chrome agar and Germ tube tests were used to detect the Candida samples. PCR, real-time-PCR, and flow cytometry tests were performed to determine the IL's rate of toxic ability. Results: Well diffusion assay revealed the diameters of the growth inhibition zones were the largest in IL with methionine and Proline amino acids. Minimum inhibitory concentration (MIC) and the Minimum fungicidal concentration (MFC) tests showed that they inhibited the growth of the C. albicans at a range from 250 µg/ml for sensitivity and 400 µg/ml for resis- tance, MIC average of all samples were 341.62 ± 4.153 µg/ml. IL reduced the expression of CDR1 and CDR2 the genes encoded by the major protein of ABC system transporter by 2.1 (P= 0.009) and 1.2 fold (P= 0.693), revealed by PCR and real time-PCR. In the flow cytometry test, there were increasing dead cells after treating with the ([Met-HCl] [PyS]) even in the most resistant strain. Conclusion: The novel IL was effective against the most clinical and standard C. albicans.

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Section: Introductionmentioning

confidence: 94%

Effect of new methionine-based ionic liquid on the CDR1 and CDR2 gene expression on sensitive and resistant strains of Candida albicans

Eslami

Ezabadi

Bayat

et al. 2023

IJM

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“…Several chiral ionic liquids derived 89 from the natural compound (+)-dehydroabietylamine 211 were reported by Ge, Yang, and their co-workers in 2023 (Scheme 38…”

Section: Scheme 35 Synthesis Of Terpene-based Chiral Ionic Liquidsmentioning

confidence: 99%

“…Several chiral ionic liquids derived 89 from the natural compound (+)-dehydroabietylamine 211 were reported by Ge, Yang, and their co-workers in 2023 (Scheme 38 ). The alkylation of the amino group of 211 with commercially available N -(bromoalkyl)trimethylammonium bromides 212a – d afforded salts 213a – d in 29–63% yield, as solids with melting points above 100 °C.…”

Section: Terpene-based Ionic Liquidsmentioning

confidence: 99%

Recent Advances in the Synthesis and Applications of Ionic Liquids Derived from Natural Products

Ranjbar-Karimi,

Marra,

Khorasani

2024

Synthesis

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Ionic liquids, nonvolatile salts featuring a melting point below 100 °C, are one of the few alternative solvents for environmentally friendly processes. However, like most molecular solvents, they are usually prepared by means of building blocks derived from fossil oil. Fortunately, an increasing number of ionic liquids are synthesized starting from renewable natural products such as sugars and amino acids. In the present review, we describe the detailed synthesis and applications of the biosourced ionic liquids reported in the literature over the last four years.1 Introduction2 Carbohydrate-Based Ionic Liquids3 Amino Acid Based Ionic Liquids4 Terpene-Based Ionic Liquids5 Miscellaneous Ionic Liquids6 Conclusion

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Chiral quaternary ammonium ionic liquids derived from natural dehydroabietylamine and their potential application in chiral molecular recognition

Cited by 2 publications

References 43 publications

Effect of new methionine-based ionic liquid on the CDR1 and CDR2 gene expression on sensitive and resistant strains of Candida albicans

Effect of new methionine-based ionic liquid on the CDR1 and CDR2 gene expression on sensitive and resistant strains of Candida albicans

Recent Advances in the Synthesis and Applications of Ionic Liquids Derived from Natural Products

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