Chiral liquid crystals as biosensing platforms

Lee, Mon-Juan; Sung, Yu Chien; Hsiao, Yu Cheng; Lee, Wei

doi:10.1117/12.2236774

Cited by 4 publications

(3 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, other LC phases have started attracting interest for specialized modes of sensing. These sensing LC states include, but are not limited to, smectics [ 17 , 46 , 47 ], cholesterics [ 48 , 49 , 50 ] and blue phases [ 51 , 52 ].…”

Section: Sensor Formatsmentioning

confidence: 99%

See 1 more Smart Citation

Thermotropic Liquid Crystal-Assisted Chemical and Biological Sensors

et al. 2017

View full text Add to dashboard Cite

In this review article, we analyze recent progress in the application of liquid crystal-assisted advanced functional materials for sensing biological and chemical analytes. Multiple research groups demonstrate substantial interest in liquid crystal (LC) sensing platforms, generating an increasing number of scientific articles. We review trends in implementing LC sensing techniques and identify common problems related to the stability and reliability of the sensing materials as well as to experimental set-ups. Finally, we suggest possible means of bridging scientific findings to viable and attractive LC sensor platforms.

show abstract

Section: Sensor Formatsmentioning

confidence: 99%

“…Nematic LCs, such as 5CB, can be turned into chiral (N* or cholesteric LCs) when mixed with chiral dopants [ 4 , 48 , 87 ]. The response of cholesteric films in contact with aqueous solutions of surfactants is rather peculiar (See Figure 13 ).…”

Section: Increasing Detection Limits and Sensitivitymentioning

confidence: 99%

Thermotropic Liquid Crystal-Assisted Chemical and Biological Sensors

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Most proposed LC biosensors are based on nematic LCs [12] and other thermotropic liquid crystals, like cholesterics [13,14], blue-phase [15], and smectics [16]. All these LCs feature a common issue, their immiscibility in aqueous media.…”

Section: Introductionmentioning

confidence: 99%

Rapid detection of pathogens using lyotropic liquid crystals

Otón¹,

Otón²,

Caño‐García³

et al. 2019

Opt. Express

View full text Add to dashboard Cite

Lyotropic liquid crystals play an important role in many biological environments, such as micelles, liposomes, and phospholipid bilayers of cell membranes. In this work, we explore the performance of lyotropic liquid crystals as biosensors for macromolecules, proteins and whole microorganisms in hydrophilic media, i.e., the natural media where these specimens exist. The aim is to detect specific targets employing simple, unpowered sensors that can be used in the field, with minimum additional equipment. A number of different structures have been explored. The novelty in this work is the inclusion of a new optical effect, flow enhanced amplification, that allows for the semiquantitative detection of microscopic targets in lyotropic liquid crystal cells using the naked eye only.

show abstract