Chipping Resistance of Nanosilica Treated Zirconia Cores Veneerd with Porcelain after Thermocycling and Cycling Loading

The chemical profiling of the main phytoconstituents of total ethanolic extract (TEE) and its different fractions of Bignonia binata leaves was dereplicated using liquid chromatographyhigh resolution-electrospray ionization-mass spectrometry (LC-HR-ESI-MS), revealed the presence of various classes of secondary metabolites; 8 phenylethanoids, 2 flavonoidal glycosides and 2 iridoids. Moreover, the hepatoprotective and nephroprotective activities of the TEE and its different fractions were investigated in CCl 4 -intoxicated rats and were compared with those of silymarin-treated group, revealing the highest potency of the EtOAc group, followed by the aqueous one in improving the CCl 4 -induced alterations in several biochemical parameters. Besides, EtOAc and aqueous fractions exhibited the most inhibition of CCl 4 -induced inflammatory mediators and improving the changes in the histopathological structures of the liver and kidney. Additionally, the EtOAc fraction demonstrated the highest total phenolic content, while TEE showed the highest amount of total flavonoid content.

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LC-MS-based identification of bioactive compounds and hepatoprotective and nephroprotective activities of Bignonia binata leaves against carbon tetrachloride-induced injury in rats

Samy

Hamed

Mahmoud

et al. 2021

Natural Product Research

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Chipping Resistance of Nanosilica Treated Zirconia Cores Veneerd with Porcelain after Thermocycling and Cycling Loading

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LC-MS-based identification of bioactive compounds and hepatoprotective and nephroprotective activities of Bignonia binata leaves against carbon tetrachloride-induced injury in rats

LC-MS-based identification of bioactive compounds and hepatoprotective and nephroprotective activities of Bignonia binata leaves against carbon tetrachloride-induced injury in rats

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