Chinolinderivate. I. Synthese substituierter 2‐Phenyl‐4‐methyl‐chinoline

John, Hanns; Noziczka, Fr.

doi:10.1002/prac.19251110106

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Rc=chcor'1

From Vinyl Ketones1

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1926

1982

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Cited by 8 publications

(2 citation statements)

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“…RCOCHsCOR' + R"NH2 + H, <3>-C=CHC0-<^3 C. QUINOLINE SYNTHESES One of the most important properties of the ß-arylamino carbonyl compounds is their ability to cyclize to form substituted quinolines. Many reviews dealing with the various methods of preparing quinolines are available, and several of them include methods involving the cyclization of saturated and unsaturated ß-arylamino ketones (12,66,69,70,92,100).…”

Section: Rc=chcor'mentioning

confidence: 99%

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The Reactions of Unsaturated Ketones and Derivatives with Amino Compounds. Amino Ketones.

Cromwell¹

1946

Chem. Rev.

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Section: Rc=chcor'mentioning

confidence: 99%

“…The yields are usually not high, because of the requirement for high temperatures to cause hydrogen or the hydrocarbon to split out. John and his coworkers (69,70) obtained very low yields of the expected 2-phenyl-4-methylquinolines on heating benzalacetone with various substituted aniline hydrochlorides at 135°C. for 5 hr.…”

Section: From Vinyl Ketonesmentioning

confidence: 99%