Chinese patients with major depression: Do concomitant pain symptoms affect quality of life independently of severity of depression?

Novick, Diego; Montgomery, William; Moneta, María Victoria; Peng, Xiaomei; Brugnoli, Roberto; Haro, Josep María

doi:10.3109/13651501.2015.1031681

Cited by 5 publications

(3 citation statements)

References 50 publications

(61 reference statements)

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“…In clinical practice, physicians should assess the severity of headache. Second, according to previous studies, PPS are associated with a poorer quality of life and a poorer treatment outcome of depression [2,4,6]. Moreover, our results showed that patients with migraine with active headache had the lowest remission rate of depression, as compared with patients with migraine with inactive headache and non-migraine subjects.…”

Section: Discussionsupporting

confidence: 75%

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Migraine with active headache was associated with other painful physical symptoms at two-year follow-up among patients with major depressive disorder

et al. 2019

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Background Few studies have investigated the associations of comorbid migraine with other painful physical symptoms (PPS) in patients with major depressive disorder (MDD) at the two-year follow-up point. This study aimed to investigate this issue. Methods At baseline, 155 outpatients with MDD were enrolled. Migraine was diagnosed at baseline according to the International Classification of Headache Disorders . At follow-up, data of 101 subjects were analyzed. The average intensities of head, bone and/or joints, back, chest, abdomen, neck and/or shoulder, general muscle, and limb pain in the past week were evaluated using a visual analog scale (VAS). At follow-up, active headache was defined as a score on the VAS > 3. Multiple linear regressions were used to investigate the associations of migraine at baseline with other PPS at follow-up. Results Compared with the migraine with inactive headache group and the non-migraine group, patients with migraine with active headache had significantly higher intensities of other PPS and a lower remission rate of depression. There were no significant differences in the pain intensities of the other seven PPS between the migraine with inactive headache group and the non-migraine group. Headache intensity was significantly correlated with the intensities of other PPS at baseline and follow-up. Migraine with active headache independently predicted other PPS after controlling for depression and anxiety at baseline. Conclusions Migraine with active headache among MDD patients could predict other PPS. Prevention and treatment of headache might help to decrease other PPS and improve the prognosis of depression. Integration of treatment for depression and headache is indicated.

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Section: Discussionsupporting

confidence: 75%

“…PPS and depression interact closely [2,3]. Among patients with major depressive disorder (MDD), PPS are common [4,5], and are associated with worse depression, an increased suicidal risk, functional impairment, a poorer quality of life, and a poorer treatment response [2–6].…”

Section: Introductionmentioning

confidence: 99%

Migraine with active headache was associated with other painful physical symptoms at two-year follow-up among patients with major depressive disorder

et al. 2019

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“…Major depressive disorder (MDD) and pain symptoms may have a shared neurobiological mechanism and may be genetically correlated [ 3 , 4 ]. Among patients with MDD, pain symptoms are common, and are associated with a greater severity of depression, a poorer treatment response, inability to achieve full remission, impaired function, a poorer quality of life, and an increased suicidal risk [ 3 , 5 – 9 ].…”

Section: Introductionmentioning

confidence: 99%

Migraine and greater pain symptoms at 10-year follow-up among patients with major depressive disorder

et al. 2018

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BackgroundNo study has investigated the associations of migraine with pain symptoms over a ten-year period among outpatients with major depressive disorder (MDD). This study aimed to investigate this issue.MethodsAt baseline, the study enrolled 290 outpatients with MDD and followed-up the patients at six-month, two-year, and ten-year time points. MDD and anxiety comorbidities were diagnosed using the Structured Clinical Interview for DSM-IV-text revision. Migraine was diagnosed based on the International Classification of Headache Disorders. The bodily pain subscale of the Short Form 36 (SF-BP) and the pain subscale (PS) of the Depression and Somatic Symptoms scale were also used. Generalized Estimating Equation models were employed to investigate the longitudinal impacts of migraine on pain symptoms.ResultsMDD patients with migraine had lower SF-BP and higher PS scores than those without. Depression, anxiety, and headache indices were significantly correlated with SF-BP and PS scores. The higher the frequency of migraine, the more often patients suffered from pain symptoms. Patients with migraine at all investigated time points suffered from pain symptoms most of the time (ranging from 60.0% to 73.7%) over the 10 years. After controlling for depression and anxiety, migraine was independently associated with a decreased SF-BP score (by 8.93 points) and an increased PS score (by 1.33 points).ConclusionMigraine was an important comorbidity associated with greater severities of pain symptoms during long-term follow-up. Migraine treatment should be integrated into the treatment of depression to improve pain symptoms and quality of life in the pain dimension.

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Analysis of glucose metabolism of 18F-FDG in major depression patients using PET imaging: Correlation of salivary cortisol and α-amylase

Wei

Xue

Guan

et al. 2016

Neuroscience Letters

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Chinese patients with major depression: Do concomitant pain symptoms affect quality of life independently of severity of depression?

Abstract: PPSs were associated with less improvement in QoL in patients receiving treatment for MDD, independent of severity of depression.

Cited by 5 publications

References 50 publications

Migraine with active headache was associated with other painful physical symptoms at two-year follow-up among patients with major depressive disorder

Migraine with active headache was associated with other painful physical symptoms at two-year follow-up among patients with major depressive disorder

Migraine and greater pain symptoms at 10-year follow-up among patients with major depressive disorder

Analysis of glucose metabolism of 18F-FDG in major depression patients using PET imaging: Correlation of salivary cortisol and α-amylase

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