Childhood recurrent abdominal pain and Helicobacter pylori infection, Islamic Republic of Iran

Alimohammadi, Hossein; Fouladi, Nasrin; Salehzadeh, Farhad; Alipour, Shirin; Javadi, Mehri

doi:10.26719/2016.22.12.860

Cited by 23 publications

(20 citation statements)

References 9 publications

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“…7 Alimohammadi et al in Iran also found gender did not have a statistical difference (p=0.8). 17 Our study found girls more dominant in the two groups: 71.1% in group 1 and 61.5% in group 2, but there is no significant difference between the two groups with p = 0.353. Hagag et al in Egypt found the mean age of H. pylori infection 8.5 ± 1.65 years, and there is no significant difference between age and H. pylori infection with p = 0.743.…”

Section: Discussioncontrasting

confidence: 58%

Correlation of Clinical Symptoms of Gastritis with H. pylori Occurrence in Children

Dewi¹,

Supriatmo²,

Arto³

et al. 2020

IJRP

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Section: Discussioncontrasting

confidence: 58%

Correlation of Clinical Symptoms of Gastritis with H. pylori Occurrence in Children

Dewi¹,

Supriatmo²,

Arto³

et al. 2020

IJRP

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“…Children with RAP had a higher H. pylori infection rate than the control group (58.6% vs 44.8%), but there was no significant difference between the RAP symptoms in H. pylori ‐positive children vs H. pylori ‐negative ones . A prospective observational study analyzed 240 Brazilian children and adolescents, mean age 9.8 years (range 4‐17) with chronic nonulcer dyspepsia, who underwent upper gastrointestinal endoscopy with biopsies. H. pylori infection was identified in 52% of cases.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

Helicobacter pylori infection in children

2017

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Helicobacter pylori infection in children differs from that in adults, from the point of view of epidemiology, host response, clinical features, related diseases, and diagnosis, as well as treatment strategies. The prevalence of H. pylori infection, in both children and adults, is decreasing in the Western World as well as in some developing countries, which contrasts with the increase in childhood asthma and allergic diseases. Recurrent abdominal pain is not specific during H. pylori infection in children. The role of H. pylori infection and failure to thrive, children's growth, type I diabetes mellitus (T1DM) and celiac disease remains controversial. The main initial diagnosis is based on upper digestive endoscopy with biopsy-based methods. Nodular gastritis may be a pathognomonic endoscopic finding of childhood H. pylori infection. The infection eradication control is based on validated noninvasive tests. The main cause of treatment failure of H. pylori infection is its clarithromycin resistance. We recommend standard antibiotic susceptibility testing of H. pylori in pediatric patients prior to the initiation of eradication therapy. H. pylori treatment in children should be based on an evaluation of the rate of eradication in the local population, a systematic use of a treatment adapted to the susceptibility profile and a treatment compliance greater than 90%. The last meta-analysis in children did not show an advantage for sequential therapy when compared to a 14-day triple therapy. Finally, the high rate of antibiotic resistance responsible for therapy failure in recent years justifies the necessity of a novel vaccine to prevent H. pylori infection in children.

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“…Clinical manifestation related to the gastrointestinal tract commonly consist of nocturnal pain, abdominal pain in the epigastric region that relief with antacid treatment, and acute or chronic gastrointestinal bleeding (hematemesis, hematochezia, or melena). 16,17 Clinical manifestation H. pylori infection non-gastrointestinal tract, especially iron-deficiency anemia, idiopathic thrombocytopenia purpura (ITP), vitamin B12 deficiency, and allergies. 18 A systematic review and meta-analysis by Muhsen et al in 2008 found H. pylori is the main factor causing iron deficiency anemia.…”

Section: Discussionmentioning

confidence: 99%

Differences of Hemoglobin and Transferrin Level between Helicobacter Pylori Gastritis and Non-Helicobacter Pylori Gastritis in Children

Hensen¹,

Supriatmo²,

Ramayani³

et al. 2020

IJRP

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Background: Gastritis can reduces the hemoglobin level. Based on previous study, gastritis resulted from Helicobacter pylori infection often correlated to anemia as the capability of Helicobacter pylori to obtain iron from hemoglobin and transferrin. Objective: To analysis the differences of hemoglobin and transferrin level between Helicobacter pylori gastritis and non-Helicobacter pylori gastritis in children. Method: A cross sectional study was conducted on outpatient and inpatient in Haji Adam Malik General Hospital, Medan and network hospitals on March-April 2020, subject ages from 2 to 18 years, diagnosed with Helicobacter pylori gastritis and non-Helicobacter pylori gastritis based on CLO test. Blood sample was taken from subjects to evaluate hemoglobin and transferrin level. Result: 54 subjects with gastrointestinal complaints were recruited. Subjects were divided into 2 groups based on CLO test, 32 subjects with Helicobacter pylori and 22 subjects without Helicobacter pylori. From blood sample analysis, mean hemoglobin and transferrin value from Helicobacter pylori group was 10.9 gr/dL and 253.5 mg/dL. Meanwhile, mean hemoglobin and transferrin value from non-Helicobacter pylori group was 10.8 gr/dL and 261.9 mg/dL. (p>0.05). Conclusion: No difference in hemoglobin and transferrin level between Helicobacter pylori gastritis and non-Helicobacter pylori gastritis in children.

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Childhood recurrent abdominal pain and Helicobacter pylori infection, Islamic Republic of Iran

Cited by 23 publications

References 9 publications

Correlation of Clinical Symptoms of Gastritis with H. pylori Occurrence in Children

Correlation of Clinical Symptoms of Gastritis with H. pylori Occurrence in Children

Helicobacter pylori infection in children

Differences of Hemoglobin and Transferrin Level between Helicobacter Pylori Gastritis and Non-Helicobacter Pylori Gastritis in Children

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