Chicken Meat Is an Infection Source of<i>Salmonella</i>Serovar Infantis for Humans in Japan

Noda, Teppei; Murakami, Koichi; Ishiguro, Yasuhisa; Asai, Tetsuo

doi:10.1089/fpd.2009.0438

Cited by 30 publications

(23 citation statements)

References 20 publications

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“…Additionally, the same trend has been observed globally, where the overall proportion of S. Infantis over the years 2001 to 2007 increased from 1.5% to 2.2% [4]. Likewise, chicken meat has been acknowledged as a significant source of S. Infantis transmitting the infection to humans [47]. To the best of our knowledge; this is the first study that links S. Infantis to poultry in Iran.…”

Section: Discussionsupporting

confidence: 59%

Molecular clonality and antimicrobial resistance in Salmonella entericaserovars Enteritidis and Infantis from broilers in three Northern regions of Iran

et al. 2013

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BackgroundMultidrug-resistant Salmonella strains are frequently encountered problems worldwide with considerable increased occurrences in recent years. The aim of this study was to investigate the occurrence and frequency of antimicrobial resistance and associated resistance genes in Salmonella isolates from broiler farms in different regions of Iran covering a time period of four years.ResultsFrom 2007 to 2011, 36 Salmonella strains were isolated from broiler farms located in three northern provinces of Iran. The isolates were serotyped, antimicrobial susceptibility tested, and characterized for antimicrobial resistance genes associated to the phenotype. Pulsed-field gel electrophoresis (PFGE) was applied for comparison of genetic relatedness.Two serovars were detected among the isolates; Salmonella enterica serovar Infantis (75%) and S. Enteritidis (25%). Thirty-four (94%) of the isolates exhibited resistance to nalidixic acid and ciprofloxacin caused by a single mutation in the quinolone resistance-determining region (QRDR) of gyrA. For all strains this mutation occurred in the codon of Asp87 leading to a Asp87-Tyr, Asp87-Gly or Asp87-Asn substitutions. All S. Infantis (n = 27) were resistant to tetracycline, spectinomycin, streptomycin, and sulfamethoxazole and harbored the associated resistance genes; tetA, dfrA14, aadA1, and sulI together with class 1 integrons. The isolates revealed highly similar PFGE patterns indicating clonal relatedness across different geographical locations.ConclusionThe data provided fundamental information applicable when launching future control programs for broilers in Iran with the aim to conserve the effectiveness of important antimicrobials for treatment in humans.

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Section: Discussionsupporting

confidence: 59%

Molecular clonality and antimicrobial resistance in Salmonella entericaserovars Enteritidis and Infantis from broilers in three Northern regions of Iran

et al. 2013

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“…Infantis is one of the most prevalent serotypes in South Korea and second in frequency among serovars [34]. In countries including Germany [35], Hungary [36], Italy [37], and Japan [38], emergence and clonal dissemination of MDR S . Infantis strains in chicken has been recent reported, and has been related to an increased incidence of human infections [31].…”

Section: Discussionmentioning

confidence: 99%

Distribution and dissemination of antimicrobial-resistant Salmonella in broiler farms with or without enrofloxacin use

Shang¹,

Wei²,

Kang³

2018

BMC Vet Res

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BackgroundSalmonella is a major zoonotic food-borne pathogen that persists on poultry farms, and animals undergo reinfection with endemic strains. The present study aimed to investigate the characteristics and dissemination of antimicrobial-resistant Salmonella within and between broiler farms that used enrofloxacin and those that did not.ResultsCloacal and environmental (litter, feed, and water) samples from two selected flocks in each of 12 farms owned by the same company were collected three times over a 30-day period of two production cycles during 2015–2016. The rate of Salmonella isolation was 7.8% (123/1584). Nine Salmonella serotypes (116 isolates) and seven untypable isolates were identified, and Salmonella Montevideo was the most prevalent serotype. Azithromycin-resistant (17.9%) and colistin-resistant (3.3%) isolates were detected, and multidrug-resistant isolates (43.1%) were also observed. No isolate was resistant to enrofloxacin or ciprofloxacin; however, intermediate resistance to enrofloxacin was significantly higher (P < 0.05) in farms that used enrofloxacin than in those that did not. The rate of multi-drug resistance among litter isolates (25/44, 56.8%) was significantly higher (P < 0.05) than that among cloacal swab (24/67, 35.8%) and feed (4/12, 33.3%) isolates. Pulsed-field gel electrophoresis (PFGE) analysis of strains of the same serotype was conducted to determine their epidemiological relationship. The PFGE types were classified into 31 groups with a 100% correlation cutoff in dendrograms for Salmonella Montevideo isolates, which showed 100% genomic identity based on age, sample type, flock, and production cycle within and between farms.ConclusionThe present study highlights the occurrence of horizontal transmission and cyclic contamination with antimicrobial-resistant Salmonella in broiler farms owned by the same company. Litter may be a good indicator of indoor environmental contamination with antimicrobial-resistant Salmonella on farms. Additionally, enrofloxacin use may be one of the factors promoting resistance towards it in Salmonella.Electronic supplementary materialThe online version of this article (10.1186/s12917-018-1590-1) contains supplementary material, which is available to authorized users.

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“…A high rate of contamination with C. jejuni, Salmonella, and S. aureus in fowl meats has been reported (22,25,29). Inspections by Japanese public institutes also have occasionally revealed the cooccurrence of C. jejuni with S. aureus in chicken meat and diarrheal stools (unpublished observations); however, whether the S. aureus isolates from diarrheal stools were MRSA was not determined.…”

Section: Discussionmentioning

confidence: 99%

Commercially Distributed Meat as a Potential Vehicle for Community-Acquired Methicillin-Resistant Staphylococcus aureus

Ogata

Narimatsu²,

Suzuki

et al. 2012

Appl Environ Microbiol

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ABSTRACTThe incidence of community-acquired methicillin-resistantStaphylococcus aureus(CA-MRSA) infection has been increasing; however, the sources of infection remain unclear. Therefore, we investigated the involvement of meat as a possible mediator of CA-MRSA infection. We examined the distribution of MRSA strains in commercially distributed raw meat samples (n= 197) and diarrheal stool samples of outpatients (n= 1,287) that were collected in Oita Prefecture, Japan, between 2003 and 2009 for routine legal inspections. Fourteen MRSA strains were isolated from three meat and 11 stool samples. Among these, seven isolates from three meat and four stool samples exhibited the same epidemiological marker profiles [coagulase type III, staphylococcal enterotoxin C, staphylococcal chromosomal cassettemec(SCCmec) type IV, ST8,spatype 606 (t1767), and toxic shock syndrome toxin-1 (TSST-1) producing type]. Furthermore, of the seven strains, three isolates from two meat samples and one stool sample collected in 2007 exhibited completely identical characteristics with respect to phage open reading frame (ORF) typing, pulsed-field gel electrophoresis, and drug susceptibility profiles. The results suggest that commercially distributed meat could play a role in the prevalence of CA-MRSA in the community.

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Chicken Meat Is an Infection Source ofSalmonellaSerovar Infantis for Humans in Japan

Abstract: These results suggest that chicken meat is an infection source of Salmonella Infantis for humans in the Kyushu-Okinawa region, Japan. The results also showed the relatively high suitability of AFLP for application to epidemiological studies of Salmonella Infantis.

Cited by 30 publications

References 20 publications

Molecular clonality and antimicrobial resistance in Salmonella entericaserovars Enteritidis and Infantis from broilers in three Northern regions of Iran

Molecular clonality and antimicrobial resistance in Salmonella entericaserovars Enteritidis and Infantis from broilers in three Northern regions of Iran

Distribution and dissemination of antimicrobial-resistant Salmonella in broiler farms with or without enrofloxacin use

Commercially Distributed Meat as a Potential Vehicle for Community-Acquired Methicillin-Resistant Staphylococcus aureus

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