“…Among the above studies, only the study by Kohyama et al (2003) considered the potential effect of body mass index (BMI) and reported that BMI was not significantly different between young and older adults in their study; other studies (Cecilio et al, 2010;Galo et al, 2006Galo et al, , 2007Kohyama et al, 2002;Kohyama & Mioche, 2004;Mioche et al, 2004b;Mishellany-Dutour et al, 2008) had not adjusted for BMI in their analysis. While accumulating data supporting the relationship between chewing behavior and energy hemostasis or body weight status have been published recently (Cassady et al, 2009;Fukuda et al, 2013;Hamada et al, 2014;Li et al, 2011;Smit et al, 2011;Zhu & Hollis, 2014aZhu et al, 2013Zhu et al, , 2014, it raises the possibility that differences in chewing behavior between young and older adults reported in previous studies (Cecilio et al, 2010;Galo et al, 2006Galo et al, , 2007Kohyama & Mioche, 2004;Kohyama et al, 2002;Mioche et al, 2004b;Mishellany-Dutour et al, 2008) may be confounded by body weight status. Therefore, studies that compare chewing behaviors between young and older adults that adjust for these confounding factors are needed; such studies are not only important for a better understanding of aging-related mastication problems, but also may provide additional information to explain for the reduced appetite in older adults, as previous studies reported that increased number of chewing cycles before swallowing results in reduced appetite (Zhu et al, 2013(Zhu et al, , 2014 and reduced food intake (Li et al, 2011;Smit et al, 2011).…”