Chest X‐ray severity score Brixia: From marker of early <scp>COVID</scp>‐19 infection to predictor of worse outcome in internal medicine wards

Carbone, Federico; Casaleggio, Alessandro; Fiannacca, Martina; Borda, F; Ministrini, Stefano; Vischi, Giulia; Carpaneto, Valeria; Sobrero, Matteo; Monti, Chiara; Stefano, Daria De; Saccomanno, Benedetta; Massone, M; Piccardo, Arianna; Calvia, Alessandro; Vischi, F; Bagnasco, Maddalena; Magnani, Ottavia; Caiti, Matteo; Cenni, E.; Ballarino, Paola; Giuntini, Patrizia; Barreca, Alessandra; Tognoni, Chiara; Pirisi, Federica; Canepa, Paolo; Cerminara, Domenico; Pelanconi, Lisa; Strozzi, Michele; Thneibat, Amedeo; Stabile, Mario; Felix, Edineia; Dasso, Selena; Casini, Cecilia; Minetti, Alberto; Poggi, A.; Gonella, Roberta; Ferrando, Fabio; Bellodi, Andrea; Ballestrero, Alberto; Barbera, Paolo; Arboscello, Eleonora; Pende, Aldo; Moscatelli, P; Cittadini, G; Montecucco, Fabrizio

doi:10.1111/eci.13908

Cited by 1 publication

(3 citation statements)

References 17 publications

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“…Along with mortality, thrombotic complications and high values of D-dimer have been reported to correlate with Brixia score [ 5 , 8 ]. A significant positive correlation between the initial Brixia score and D-dimer value was found previously (r = 0.45, p < 0.000) [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, as a standard part of the initial diagnosis of COVID-19, chest radiography (CXR) is performed primarily, as well as computed tomography (CT) of the chest [ 1 , 2 , 4 ]. CXR has verified its role as a crucial tool in COVID-19 assessment due to its practicability, especially in emergency units [ 5 ]. The basic characteristics of COVID-19 on lung radiography usually include bilateral lung opacities and an accentuated interstitial pattern [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…Multiple studies have validated Brixia score and also investigated its predictive value for patients with a diagnosis of COVID-19 pneumonia. It was found that Brixia score is associated with death and atherothrombotic complications during hospitalization and after hospital discharge [ 5 ]. Others reported that higher values of Brixia score are connected with intubation, demand for non-invasive ventilation and fatal outcome, setting a cut-off score of six as intubation predictor [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

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Brixia Chest X-ray Score, Laboratory Parameters and Vaccination Status for Prediction of Mortality in COVID-19 Hospitalized Patients

Nukovic,

Opancina,

Zdravkovic

et al. 2023

Diagnostics

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Chest X-ray has verified its role as a crucial tool in COVID-19 assessment due to its practicability, especially in emergency units, and Brixia score has proven as a useful tool for COVID-19 pneumonia grading. The aim of our study was to investigate correlations between main laboratory parameters, vaccination status, and Brixia score, as well as to confirm if Brixia score is a significant independent predictor of unfavorable outcome (death) in COVID-19 patients. The study was designed as a cross-sectional multicentric study. It included patients with a diagnosed COVID-19 infection who were hospitalized. This study included a total of 279 patients with a median age of 62 years. The only significant predictor of unfavorable outcome (death) was Brixia score (adjusted odds ratio 1.148, p = 0.022). In addition, the results of the multiple linear regression analysis (R2 = 0.334, F = 19.424, p < 0.001) have shown that male gender (B = 0.903, p = 0.046), severe COVID-19 (B = 1.970, p < 0.001), and lactate dehydrogenase (B = 0.002, p < 0.001) were significant positive predictors, while albumin level (B = −0.211, p < 0.001) was a significant negative predictor of Brixia score. Our results provide important information about factors influencing Brixia score and its usefulness in predicting the unfavorable outcome (death) of COVID-19 patients. These findings have clinical relevance, especially in epidemic circumstances.

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Section: Discussionmentioning

confidence: 99%