2020
DOI: 10.1007/s11739-020-02561-3
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Chest X-ray findings in a large cohort of 1117 patients with SARS-CoV-2 infection: a multicenter study during COVID-19 outbreak in Italy

Abstract: To describe radiographic key patterns on Chest X-ray (CXR) in patients with SARS-CoV-2 infection, assessing the prevalence of radiographic signs of interstitial pneumonia. To evaluate pattern variation between a baseline and a follow-up CXR. 1117 patients tested positive for SARS-CoV-2 infection were retrospectively enrolled from four centers in Lombardy region. All patients underwent a CXR at presentation. Follow-up CXR was performed when clinically indicated. Two radiologists in each center reviewed images a… Show more

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Cited by 13 publications
(26 citation statements)
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“…The recommendation to limit the use of CT studies in the time of a pandemic surge is also supported by societal guidelines [4,5]. Lung ultrasound (LUS) and chest radiography (CXR) are valid alternatives to be applied in the frontline [1,[6][7][8][9][10][11][12][13][14]. Particularly, LUS demonstrated highly feasible and sensitive for COVID-19 pneumonia, with a specificity that increases during the peaks of prevalence [15].…”
Section: Introductionmentioning
confidence: 99%
“…The recommendation to limit the use of CT studies in the time of a pandemic surge is also supported by societal guidelines [4,5]. Lung ultrasound (LUS) and chest radiography (CXR) are valid alternatives to be applied in the frontline [1,[6][7][8][9][10][11][12][13][14]. Particularly, LUS demonstrated highly feasible and sensitive for COVID-19 pneumonia, with a specificity that increases during the peaks of prevalence [15].…”
Section: Introductionmentioning
confidence: 99%
“…Chest computed tomography (CT) and chest radiography (chest X-ray, CXR) are the imaging modalities generally performed to detect lung abnormalities in early infection, and to assess the severity and monitor the progression of COVID-19 pneumonia [ 25 , 26 ]. CT has been mainly used for diagnosing COVID-19 pneumonia [ 27 , 28 , 29 ].…”
Section: Chest X-raymentioning
confidence: 99%
“…CT has been mainly used for diagnosing COVID-19 pneumonia [ 27 , 28 , 29 ]. This is due to the experience of China, where access to CT was relatively easy at the outbreak of the pandemic [ 28 ], and the low sensitivity of CXR in revealing pulmonary involvement, particularly in the early stage of the disease [ 25 , 27 ]. Using RT-PCR as the gold standard, the sensitivity of CRX, which depends not only on the disease stage, but also on its severity, the prevalence of COVID-19 in the area, and the expertise of radiologists, with possible support of artificial intelligence (AI), differs widely from 41.7 to 90% and is still lower than CT (60 to 98%) [ 30 , 31 , 32 ].…”
Section: Chest X-raymentioning
confidence: 99%
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