Chest wall reconstruction using implantable cross-linked porcine dermal collagen matrix (Permacol)

Lin, Shoutzu; Kastenberg, Zachary J.; Bruzoni, Matías; Albanese, Craig T.; Dutta, Sanjeev

doi:10.1016/j.jpedsurg.2012.05.002

Cited by 36 publications

(38 citation statements)

References 12 publications

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“…A retrospective study performed on 5 patients described the use of biologic mesh as a safe and dependable alternative to synthetic prostheses and tissue repair in pediatric chest wall reconstruction [10]. …”

Section: Discussionmentioning

confidence: 99%

Primary malignant chest wall tumors: analysis of 40 patients

Bagheri

Haghi

Kalantari

et al. 2014

J Cardiothorac Surg

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BackgroundPrimary chest wall tumors originate from different constructions of thoracic wall. We report our multidisciplinary experience on primary thoracic tumor resection and thoracic reconstruction, the need to additional therapy and evaluating prognostic factors affecting survival.MethodsWe performed a retrospective review of our prospectively maintained database of 40 patients treated for malignant primary chest wall tumor from 1989 to 2009. Patients were evaluated in terms of age, sex, clinical presentation, type of imaging, tissue diagnosis methods, pathology, surgical technique, early complications, hospital mortality, prevalence of recurrence and distant metastases, additional treatment, 3 years survival and factors affecting survival.ResultsMale/Female (F/M) = 1, with median age of 43.72 years. Mass was the most common symptoms and the soft tissue sarcoma was the most common pathology. Resection without reconstruction was performed in 5 patients and Thirty-five patients (87.5%) had extensive resection and reconstruction with rotatory muscular flap, prosthetic mesh and/or cement. Overall, 12.5% (5/40) of patients received neoadjuvant therapy and 75% (30/40) of patients were treated with adjuvant therapy. The 3-year survival rate was 65%. Recurrences occurred in 24 patients (60%), 14 developed local recurrences, and 10 developed distant metastases. The primary treatment modality for both local and distant recurrences was surgical resection; among them, 10 underwent repeated resection, 9 adjuvant therapy and 5 were treated with lung metastasectomy. The most common site of distant metastasis was lung (n = 7). Factors that affected survival were type of pathology and evidence of distant metastasis.ConclusionSurgery with wide margin is the safe and good technique for treatment of primary chest wall tumors with acceptable morbidity and mortality.

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Section: Discussionmentioning

confidence: 99%

Primary malignant chest wall tumors: analysis of 40 patients

Bagheri

Haghi

Kalantari

et al. 2014

J Cardiothorac Surg

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“…Recently, a small case series [19] described the use of Permacol in pediatric chest wall reconstructions with good short-term results. Concerning abdominal wall reconstruction, Richards et al [20] and Pentlow et al [21] described the use of Permacol in pediatric renal transplant recipients with donor size discrepancies.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of a Porcine Dermal Collagen (Permacol) Implant for Abdominal Wall Reconstruction in a Pediatric Multitrauma Patient

Melnik

Mnouskin

Kurzbart

et al. 2014

Case Reports in Emergency Medicine

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The presence of a contaminated surgical field in abdominal wall defects caused by trauma presents a challenge for surgeons. Both primary suture and synthetic meshes are strongly discouraged as surgical treatments in such cases. We describe the use of a porcine dermal collagen (Permacol) implant in an eight-year-old patient with multiple injuries. Three months after discharge, the child remains well with good cosmetic results. He is free of pain and has returned to full activity levels with complete wound closure and without any evidence of residual hernia. In conclusion, our experience indicates that the use of Permacol can be considered an efficient technique for reconstructing an infected abdominal wall defect of a pediatric multitrauma patient.

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“…Thus, chest wall reconstruction at the same time as the resection favours early extubation and reduces the risk of mortality [4,16]. Lin et al [17] reported their experience with the biological mesh Permacol (Covidien, Mansfield, MA, USA) in 5 children with chest wall malignancy to determine the safety of the biological mesh in children with no postoperative complications. The Gore® DualMesh® biomaterial, an expanded PTFE prosthesis, was used in 11 cancer patients [18].…”

Section: Discussionmentioning

confidence: 99%