“…The boy was treated according to the Nordic Pediatric Hematology and Oncology group NOPHO-88 AML protocol. 14 One month after one course of thioguanine, cytosine Specific PCR analysis arabinoside and etoposide, his bone marrow was in remission. He then received three further courses of chemotherapy To show that the chimerical product determined by the ART-PCR procedure was present in the leukemic cells, we conbefore bone marrow harvest and a subsequent autologous bone marrow transplantation in October 1990.…”
A novel variant of the chimerical MLL-AF10 mRNA transcript method developed from an asymmetrical PCR method was detected in a pediatric patient with acute myeloid leukemia previously described by us.
“…The boy was treated according to the Nordic Pediatric Hematology and Oncology group NOPHO-88 AML protocol. 14 One month after one course of thioguanine, cytosine Specific PCR analysis arabinoside and etoposide, his bone marrow was in remission. He then received three further courses of chemotherapy To show that the chimerical product determined by the ART-PCR procedure was present in the leukemic cells, we conbefore bone marrow harvest and a subsequent autologous bone marrow transplantation in October 1990.…”
A novel variant of the chimerical MLL-AF10 mRNA transcript method developed from an asymmetrical PCR method was detected in a pediatric patient with acute myeloid leukemia previously described by us.
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