Chemotherapeutics in Implant Dentistry

Effect of six different peri‐implantitis disinfection methods on in vivo human oral biofilm

“…the ability to bind to hard and soft tissue with slow release (Mandel 1994). Chlorhexidine gluconate has shown to inhibit plaque formation and improve gingival indices around natural teeth and implants (Zablotsky 1992b; Hayek et al 2005; Schwarz et al 2005, 2006a; Trejo et al 2006; Bürgers et al 2008a). The mechanism of action of Listerine involves bacterial cell wall destruction, bacterial enzymatic inhibition, and extraction of bacterial lipopolysaccharides (Mandel 1994).…”

“…However, because treatment recommendations remain unclear, further evaluation and clinical trials seem to be necessary for finding treatment regimes for peri‐implantitis and mucositis (Klinge et al 2002; Roos‐Jansaker et al 2003; Grusovin et al 2008; Kotsovilis et al 2008; Lindhe & Meyle 2008; Renvert et al 2008). In general, the adjunctive use of chemical agents or antibacterial mouth rinses has been shown to enhance the outcome of the mechanical treatment of peridontitis and may even aid successful peri‐implantitis therapy (Zablotsky et al 1991, 1992b; Dennison et al 1994; Roos‐Jansaker et al 2003; Schwarz et al 2005, 2006b; Lindhe & Meyle 2008; Renvert et al 2008). Several reports have demonstrated the healing potential of peri‐implant tissues after suppressing peri‐implant microbial plaque (Zablotsky et al 1991, 1992a; Dennison et al 1994; Mombelli 2002; Roos‐Jansaker et al 2003; Schwarz et al 2005; Lindhe & Meyle 2008).…”

Complex systematic review ‐ Perioperative antibiotics in conjunction with dental implant placement

“…Any disagreement during the screening process were resolved by discussion between the two reviewers or, if necessary, by a third party (ST). Studies excluded at this stage, and Esposito et al (2003) x More recent publication by same author found Esposito et al (1998) x Not a systematic review Garg (2004) x Not a systematic review Garg (2001) x Not a systematic review Garg (1992) x Not a systematic review Greenstein et al (2008) x Not a systematic review Heitz-Mayfield et al (2014) x Not a systematic review Lawler & Goss (2005) x Not a systematic review Pjetursson et al (2012) x Out of topic Pye et al (2009) x Not a systematic review Rizzo et al (2010) X Schwartz & Larson (2007) X Sennerby (1998) x Not a systematic review X x Not a systematic review Trieger (1999) x Not a systematic review Zablotsky (1993) x Not a systematic review…”

The Use of CO2 Laser in the Treatment of Peri-implantitis

“…6 To enhance the results, some investigators have suggested that it is necessary to decontaminate defective implant surfaces. 6,[10][11][12][13] Several different methods of implant decontamination have been proposed. 13 Neither subgingival irrigation with local disinfectants 12,14,15 nor local antibiotic therapy with tetracycline fibers provided conclusive therapeutic effects.…”