Chemosensory Contributions of E-Cigarette Additives on Nicotine Use

Johnson, Noor; Patten, Theresa; Ma, Minghong; Biasi, Mariella De; Wesson, Daniel W.

doi:10.3389/fnins.2022.893587

Cited by 5 publications

(2 citation statements)

References 213 publications

(299 reference statements)

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“…A key finding of our study is that e-cigarette users face the highest odds of developing sensory disorders compared to other groups. The review of Johnson et al 14 demonstrated that little is known about the sensory effects of e-cigarettes. However, as more nicotine is added to e-cigarette liquids, users increasingly perceive irritation and bitterness over time 14 .…”

Section: Discussionmentioning

confidence: 99%

“…The review of Johnson et al 14 demonstrated that little is known about the sensory effects of e-cigarettes. However, as more nicotine is added to e-cigarette liquids, users increasingly perceive irritation and bitterness over time 14 . This revelation heightens concerns about the potential health risks tied to e-cigarette use, especially given the growing trend of use among adolescents and young adults 11 .…”

Section: Discussionmentioning

confidence: 99%

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Tobacco products and sensory health: An assessment of taste and smell disorders using 2021 NHIS data

Bin Hamdan,

AlAmri,

Aldosari

2024

Tob. Induc. Dis.

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INTRODUCTION This study aims to assess the relationship between use of tobacco products and taste and smell disorders. METHODS A secondary dataset analysis of cross-sectional data from the National Health Interview Survey (NHIS) 2021 survey cycle, a nationally representative annual cross-sectional interview of non-institutionalized US civilians, was used. Participants' senses of smell and taste are assessed using self-reported questions. Participants were categorized into five groups based on their tobacco use: non-tobacco users; cigarettes only; e-cigarettes only; cigar, pipe, or smokeless tobacco; and poly-tobacco product users. Disorders were defined as any self-reported difficulty in smelling, tasting, or reporting unpleasant odors or persistent tastes. Weighting procedures were used to estimate the national prevalence of taste, smell, and other disorders, stratified by tobacco products used. Adjusted logistic regression models were used to determine the association between tobacco products used and taste or smell compared to non-tobacco users. RESULTS A total of 40.2 million US adults reported experiencing smell or taste disorders. Nearly one in 10 adults reported a taste disorder (9.8%), and 13.4% indicated a smell disorder. The prevalence of taste or smell disorder was higher among females (17.5%), Hispanics (19.5%), individuals identified as ‘other’ racial minorities (21.1%), and lower income groups (21%). Compared to non-tobacco users, the highest odds of experiencing smell or taste disorders were among poly-tobacco product users (adjusted odds ratio, AOR=1.44; 95% CI: 1.31–1.58), followed by e-cigarette-only users (AOR=1.38; 95% CI: 1.02–1.87), cigarette-only smokers (AOR=1.17; 95% CI: 1.04–1.32), and users of cigars, pipes, or smokeless tobacco (AOR=1.15; 1.00; and 1.33; respectively). CONCLUSIONS Tobacco product use was associated with an increased risk of smell and taste disorders. The rising use of e-cigarettes among adolescents and young adults is particularly concerning given the limited understanding of the sensory effects of e-cigarettes and their growing popularity among younger populations. The study findings highlight the need for interventions aimed at reducing tobacco use of all kinds.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Tobacco products and sensory health: An assessment of taste and smell disorders using 2021 NHIS data

Bin Hamdan,

AlAmri,

Aldosari

2024

Tob. Induc. Dis.

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Smoking reduction using electronic nicotine delivery systems in combination with nicotine skin patches

et al. 2023

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Rationale Electronic nicotine delivery systems (ENDS) are used by smokers seeking to reduce combustible cigarette (CC) use, but the role of nicotine replacement vs. behavioral and sensory factors is still poorly understood. We hypothesized that providing nicotine from ENDS in addition to nicotine skin patches would promote smoking reduction relative to non-nicotine control ENDS. Objectives To assess the effects on smoking behavior of using nicotine vs. placebo ENDS in smokers using nicotine vs. placebo patches. Methods Ninety-four daily smokers were enrolled in a study that randomly assigned them to receive ENDS with nicotine vs. without nicotine and skin patches with vs. without nicotine. Smoking reduction and cessation were assessed over an 8-week period by self-report and by expired air carbon monoxide (CO) measurements. The primary outcome was defined as reduction in expired air CO. Results The use of nicotine in ENDS led to significant reductions in smoking (ENDS nicotine vs. placebo difference in CO change = −9.2 ppm; 90% CI (−1.5 ppm, −16.9 ppm)) and was highly correlated with reductions in self-reported cigarettes per day (r=0.6). The effect of nicotine in nicotine patches was not statistically significant (patch nicotine vs. placebo difference in CO change = −0.1 ppm; 90% CI (−7.8 ppm, 7.6 ppm)). Conclusions The presence of nicotine in ENDS was associated with a large reduction in smoking. Additional studies will be needed to determine whether there may be additive effects of nicotine ENDS and nicotine patches on smoking abstinence.

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Prediction of the transport, deposition, and absorption of multicomponent E-cigarette aerosols in a subject-specific mouth-to-G10 human respiratory system

Sperry

Feng

Zhao

et al. 2023

Journal of Aerosol Science

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Chemosensory Contributions of E-Cigarette Additives on Nicotine Use

Cited by 5 publications

References 213 publications

Tobacco products and sensory health: An assessment of taste and smell disorders using 2021 NHIS data

Tobacco products and sensory health: An assessment of taste and smell disorders using 2021 NHIS data

Smoking reduction using electronic nicotine delivery systems in combination with nicotine skin patches

Prediction of the transport, deposition, and absorption of multicomponent E-cigarette aerosols in a subject-specific mouth-to-G10 human respiratory system

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