Chemoprofile and bioactivities of Taverniera cuneifolia (Roth) Arn.: A wild relative and possible substitute of Glycyrrhiza glabra L.

In vitro anti-rotavirus activity of polyphenol compounds isolated from the roots of Glycyrrhiza uralensis

“…10 These constituents of G. uralensis have been found to exhibit anticancer, anti-diabetic, anti-inflammatory, anti-malarial, anti-bacterial, antioxidant, and estrogenic properties. 11,12 Also, isolated glycyrrhizin and derivatives thereof have shown activity against a variety of viruses, including herpes simplex type 1 (HSV-1); 13 hepatitis A, B, and C viruses (HAV, HBV, and HCV); 14 HIV-1; 15 and influenza viruses. 16 anti-rotavirus activities of polyphenols isolated from the plant have not previously been tested.…”

Somatic embryogenesis, regeneration and in vitro production of glycyrrhizic acid from root cultures of Taverniera cuneifolia (Roth) Arn.

“…Dry plates were examined under UV light (254 nm) and scanned using CAMAG TLC scanner III. UV spectra, R f values,% Area under curve (AUC) and λ max of each band were documented as described by Zore et al (2008).…”

“…This genus is endemic to parts of Africa and Southern Asian countries and commonly known as commercial licorice (Stadler et al 1994;Naik 1998;Zore 2005). Because this plant is known to contain glycyrrhizic acid (GA), it is regarded as a substitute for Glycyrrhiza glabra (Zore et al 2008). GA is a medicinally important triterpene glycoside found in leguminous plants like G. glabra L. (common licorice), Glycyrrhiza uralensis Fisch.…”

“…The GA content varies among different sources; it is 16% in G. glabra, 6-14% in G. uralensis (Chung et al 2001) and 13% in Taverniera cuneifolia (Zore et al 2008). Because of its GA content, G. glabra is in high demand in medicine, including Ayurvedic medicine, which out-weighs its supply by several-fold.…”

Assessment of median lethal dose and anti-mutagenic effects of Glycyrrhiza glabra root extract against chemically induced micronucleus formation in Swiss albino mice

“…1 The roots and rhizomes of Glycyrrhiza glabra have been widely used in medicines for its unique and diverse pharmacological properties viz., antiviral, anticancer, anti-ulcer, anti-diabetic, antiinfl ammatory, immunostimulant, anti-allergenic, etc. 2,3 In addition, the roots are also used as a fl avoring and sweetening agents with tobacco chewing, chewing gums, candies, toothpaste, and beverages. 4 Phytochemical investigations have demonstrated that the major bioactive components of Glycyrrhiza glabra roots are fl avonoids and pentacyclic triterpene saponin, Alkaloids, Glycosides, etc.…”