Chemistry of Porous Silicon

doi:10.1002/9783527641901.ch6

Cited by 6 publications

(3 citation statements)

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“…Silicon dioxide is nontoxic and biocompatible, and based on these features it has been proposed as material for drug delivery in cell culture models and for tissue engineering [29]. In addition, silicon offers a flexible surface chemistry that allows one to link bioconjugators such as collagen [30]. Collagen is an attractive tool for biomedical applications as it is the most abundant protein in mammalian tissues [31].…”

Section: Introductionmentioning

confidence: 99%

Silicon microgrooves for contact guidance of human aortic endothelial cells

Fernández‐Castillejo

Formentı́n

Catalán

et al. 2017

Beilstein J. Nanotechnol.

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Background: Micro- and nanoscale substrates have been fabricated in order to study the influence of the topography on the cellular response. The aim of this work was to prepare different collagen-coated silicon substrates displaying grooves and ridges to mimic the aligned and elongated endothelium found in linear vessels, and to use them as substrates to study cell growth and behaviour. Results: The influence of groove-shaped substrates on cell adhesion, morphology and proliferation were assessed, by comparing them to flat silicon substrates, used as control condition. Using human aortic endothelial cells, microscopy images demonstrate that the cellular response is different depending on the silicon surface, when it comes to cell adhesion, morphology (alignment, circularity and filopodia presence) and proliferation. Moreover, these structures exerted no cytotoxic effect. Conclusion: The results suggest that topographical patterning influences cell response. Silicon groove substrates can be used in developing medical devices with microscale features to mimic the endothelium in lineal vessels.

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Section: Introductionmentioning

confidence: 99%

Silicon microgrooves for contact guidance of human aortic endothelial cells

Fernández‐Castillejo

Formentı́n

Catalán

et al. 2017

Beilstein J. Nanotechnol.

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“…This process serves two primary purposes: first, to prevent uncontrolled oxidation of PSi in water-based solutions at room temperature, and second, to enhance the infiltration of water-based solutions containing Na + Clion pair within the PSi structure. The stability of silicon dioxide in neutral or slightly acidic solutions, such as the deionized water (DIW)-based NaCl solution used in this study (with a pH ~5.5), is a contributing factor [14]. In addition, silicon dioxide exhibits hydrophilic properties, as evidenced by the decrease in contact angle from 110˚C for silicon to 13.5˚C for silicon dioxide [15].…”

Section: Resultsmentioning

confidence: 99%

Highly sensitive refractive index sensing based on nanostructured porous silicon interferometers

Thuy Van,

Thanh Son,

Thanh Binh

et al. 2024

Comm. Phys.

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In this study, we present the experimental evidence demonstrating the utility of electrical double layer (EDL)-induced ion accumulation, using sodium (Na+) ion in water as model substances, on a negatively charged nanostructured surface, specifically thermally grown silicon dioxide (SiO2). This novel approach, termed Ion Surface Accumulation (ISA), aims to enhance the performance of nanostructured porous silicon (PSi) interferometers in optical refractometric applications. The experimental results show that the electrical double layer-induced ion surface accumulation (EDL-ISA) on oxidized PSi interferometers enables remarkable amplification of the interferometer output signal (the spectral interferogram), even when the bulk refractive index variation is below 10-3 RIU. This substantial signal enhancement translates into an increase in sensitivity of up to two orders of magnitude, facilitating the reliable measurement of refractive index variations with both a detection limit (DL) and resolution (R) as low as 10-4 RIU. This achievement elevates the performance of PSi interferometers in photonics and plasmonics-based refractive index platforms.

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“…Surface functionalization is a logical step for the protection of devices and has been extensively applied to PSi surfaces. 8 , 9 …”

Section: Introductionmentioning

confidence: 99%