Chemistry of Palmar Sweat

Lobitz, Walter C.; Mason, Harold L.

doi:10.1001/archderm.1948.01520180124013

Cited by 43 publications

(3 citation statements)

References 11 publications

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“…There exists in the sweat gland an anatomical differentiation which might serve this purpose. At the base the coiled tubule is lined with a single layer of epithelial cells, while the duct has a double layer of epithelial cells with a hyaline layer along the luminal border of the cells (15). If it be assumed that these are regions of greater and lesser permeability to urea, respectively, and that a reabsorption of water takes place through the wall of the duct, the phenomenon would be explained.…”

Section: Discussionmentioning

confidence: 99%

Urea Excretion in Human Sweat as a Tracer for Movement of Water Within the Secreting Gland

Schwartz

Thaysen

Dole

1953

Journal of Experimental Medicine

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Previous workers have found that the concentration of urea in human sweat exceeds the concentration of urea in plasma. This fact has been confirmed in the present work and extended by measurements of the concentrations of urea in the sweat and the corresponding concentrations of urea in the plasma over a range of 25- fold variation in the latter. An analysis of the data showed that the ratio of the concentration of urea in sweat to the concentration of urea in plasma, S/P, was independent of the plasma concentration, independent of the absolute flux of urea or water, and independent of the calculated energy expenditure. Two experiments showed that the concentration of urea in sweat followed a rising concentration in plasma with a time lag of approximately 5 minutes; this fact indicates that the accumulation of urea in sweat is a continuous process which is in operation during the observed discharge. These observations suggest that urea is carried into the gland in some precursor solution and subsequently raised to a higher concentration by the reabsorption from this solution of a constant fraction of the water.

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Section: Discussionmentioning

confidence: 99%

Urea Excretion in Human Sweat as a Tracer for Movement of Water Within the Secreting Gland

Schwartz

Thaysen

Dole

1953

Journal of Experimental Medicine

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“…Continuous monitoring is strongly requested. On the other hand, it is reported that blood glucose which is not incorporated by the liver is excreted in sweat if a higher blood sugar level continues [1]. This indicates chronic hyperglycemia non-invasively.…”

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confidence: 99%

A Wearable Biosensor with Biocompatible Polymers

Shirai¹,

Chu²,

Kudo³

et al. 2008

Meet. Abstr.

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“…Acker mann (12) was probably the first to suggest it. Later, Lobitz & Mason (13) found that many constituents of sweat were more concentrated at low rates of sweating. They suggested that at these slow rates there was greater op portunity for the ducts to reabsorb water.…”

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confidence: 99%

Dermatology: The Eccrine Sweat Glands

Wc¹,

Rl²

1961

Annu. Rev. Med.

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Although much is known about the human eccrine sweat glands as a re sult of extensive studies carried out during the past half century, surprisingly little can be stated concerning the function of these organs without fear of contradiction. This situation has arisen for three major reasons: (a) It is now known that during active function the cellular structure of the eccrine sweat gland is undergoing significant alterations. (b) The function of the sweat gland is, in great part, dependent on the state of both the external and internal environment. (Careful control of both of these variables is essential to an experimental situation from which interpretable information is to be derived.) (c) Interpret�tion of the function of the sweat gland is considerably influenced by the method of sweat collection, the area from which the sweat is collected and the method employed to produce sweating.This review will not deal with specific diseases of the eccrine sweat gland.Nor will it be concerned with the alterations in structure and function of the sweat apparatus that occur when the skin itself is altered by disease. We will not emphasize environmental physiology and the problems of acclimatiza tion. The reader is referred to a most excellent and comprehensive review by . Weiner & Hellmann (53) on the total eccrine and apocrine sweat gland story.The interested reader, too, should refer to the recent book edited by Yoshi� mura, Ogata & Itoh on climatic physiology (54).In this review it is our hope to integrate, as much as possible, the many aspects now known of eccrine sweat gland structure and function in health and associated with non-cutaneous medical disease. In this way perhaps the interpretations of isolated findings on this subject will be made easier. In addition, we will take opportunities, too. to emphasize the many areas in which further investigative studies may be especially fruitful.On the basis of location, two types of eccrine glands can be differentiated: those on the palms and soles which respond primarily to mental work and emotional stimuli, and those in the remainder of the skin which act mainly in a thermoregulatory role. All eccrine sweat glands are innervated by sym pathetic fibers, but the secretion is induced by cholinergic agents. The nerve

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Chemistry of Palmar Sweat

Cited by 43 publications

References 11 publications

Urea Excretion in Human Sweat as a Tracer for Movement of Water Within the Secreting Gland

Urea Excretion in Human Sweat as a Tracer for Movement of Water Within the Secreting Gland

A Wearable Biosensor with Biocompatible Polymers

Dermatology: The Eccrine Sweat Glands

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