Chemistry and biological activities of C. longa

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“…Among them methanol does not provide the required resolution/selectivity for the separation of curcuminoids 10 . The use of tetrahydrofuran instead of acetonitrile reverses the order elution of the curcuminoids 5,8,17 . Moreover, acetonitrile is the solvent of choice because of its low wavelength transparency, polarity, and intermediate position between methanol and tetrahydrofuran 18 .…”

“…Many methods are available for the assay of curcumin. They include direct fluorimetric, spectroscopic (IR, NMR, MS) and HPLC methods 5 . However, HPLC methods are widely used considering ease and sensitivity.…”

Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified Aromatic-Turmerone (AR)

“…Furthermore turmeric widely consumed as food additive and medicine, are believed to possess antimicrobial, antifungal, antiviral, anti-inflammatory activities, wound healing, insecticidal activity, anti-platelet effects, anti-cancer, anti-inflammatory, antioxidant, limit fungal growth and toxin production properties. [8][9][10][11][12][13][14][15][16][17][18] Previous studies had shown that AR isolated from turmeric could induce apoptosis in human leukemia cells 19 and murine leukemia cells. 20 Moreover, AR can be employed as an agent in functional cosmetics to develop safe and effective skin-whitening treatments.…”

PENGARUH PROSES PENGERINGAN RIMPANG TEMULAWAK (Curcuma xanthorriza ROXB) TERHADAP KANDUNGAN DAN KOMPOSISI KURKUMINOID

“…Telah dilaporkan bahwa bahan alam ini dikonsumsi dalam bentuk campuran senyawa diarilheptanoid, yakni kurkumin (1), demetoksi kurkumin (2), dan bisdemetoksikurkumin (3). Zat warna kuning alami yang diperbolehkan untuk pewarna makanan ini telah cukup lama dikenal sebagai obat batuk, obat gangguan hati, rematik, dan sinusitis (review: Jayaprakasha, 2005). Keberadaan gugusan phenolik pada ketiga senyawa tersebut dilaporkan juga menyebabkan aktivitas antioksidan yang kuat pada system biologis (Ahsan, 1998), sehingga dapat mencegah penyakit-penyakit yang berhubungan dengan reaksi peroksidasi.…”

“…Kurkuminoid diisolasi dengan pelarut etanol 95% mengingat metode ini telah terbukti efektif untuk mengekstrak kurkuminoid (Photitirat, 2004;Jayaprakasha, 2005). Secara tampilan fisik, powder kurkuminoid yang telah terbebas lemaknya dari bahan segar dan simplisia tidak ada bedanya.…”