ChemInform Abstract: α‐Glucosidase Inhibitory Monoacylated Polyhydroxytriterpenoids from the Fruits of Barringtonia racemosa.

Abstract

-Glucosidase Inhibitory Monoacylated Polyhydroxytriterpenoids from the Fruits of Barringtonia racemosa. -Monoacylated polyhydroxy triterpenoids racemosol C (I) and racemosol D (II) encountered in this study are unusual and exhibit excellent -glucosidase inhibition and moderate cytotoxicity. -(PONNAPALLI*, M. G.; SUKKI, S.; ANNAM, S. C. V. A. R.; ANKIREDDY, M.; TIRUNAGARI, H.; TUNIKI, V. R.; BOBBILI, V. V. P.; Tetrahedron Lett. 56 (2015) 12, 1570-1574, http://dx.

Site-selective biotransformation of ursane triterpenes by Streptomyces griseus ATCC 13273

“…Pentacyclic triterpenes (PTs) are bioactive natural products, which display a remarkable spectrum of biological activities, such as anti-tumor, anti-HIV, anti-microbial, anti-diabetic, and anti-inammatory activities. [1][2][3][4] The substitution of hydroxyl or carbonyl groups to the methyl or methenyl carbons, respectively, of the skeleton greatly enrich the structural diversity 2,5,6 and is also essential for the biological activities and structural modication of PTs. [7][8][9] Herein, the research on the structural modication of PTs was focused on the functionalization of the unactivated C-H bonds on the skeleton; it could also enrich the structural diversities and generate more effective and/or less toxic derivatives.…”