ChemInform Abstract: The Use of Inorganic Materials to Control or Maintain Immobilized Enzyme Activity

Abstract

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Electrochemical Biosensors: Electrode Development, Materials, Design, and Fabrication

“…Electron transfer is facilitated because gold nanoparticles possess attractive characteristics, such as high surface‐to‐volume ratio, high surface energy, the ability to decrease protein‐metal particle distance, and to function as electron‐conducting pathways. The three most common applications of gold nanoparticles, particularly in biosensing applications, are electrochemical biosensors, optical biosensors, and piezoelectric biosensors .…”

“…Moreover, Crumbliss et al reported the preparation of two immobilized enzyme electrodes. They used horseradish peroxidase which was absorbed by gold nanoparticles.…”

Bio-inspired Silica Nanomaterials for Biomedical Applications

“…Like contrast agents, ideal biosensors should be highly sensitive, specific, rapid, and inexpensive. [103][104][105] In such biosensors it is ideal to have well-formed regular pores to ensure quick diffusion of the analytes to the sensing sites. 94 A variety of processes have been investigated to achieve signal transduction including electrochemical processes, [95][96][97][98] field-effect transistor processes, 99 and optical processes (absorption, fluorescence, interference).…”

Electrochemically-driven and dynamic enhancement of drug metabolism via cytochrome P450 microsomes on colloidal gold/graphene nanocomposites

“…21 It has been shown that decorated Au NPs could be used to simulate the appropriate bioenvironment to maintain redox proteins in their native state. 22 In the past years, our laboratory has fabricated a biocompatible film by entrapping CYP 2B6 isozyme microsomes into Au-chitosan, and realized the direct electrochemistry of CYP 2B6 and applied electrocatalysis toward three common clinical drugs. 23 Au NPs have also been used as electron transfer mediators and as 'electric wires' for enhancing the electron transfer rate between immobilized redox proteins and the electrode surface.…”