ChemInform Abstract: The Synthesis of Substituted 2‐Aryl 4(3H)‐Quinazolinones Using NaHSO₃/DMA. Steric Effect upon the Cyclization‐Dehydrogenation Step.

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Thermal and magnetic behaviour of 5-chloro-2-nitrobenzoates of Co(II), Ni(II) and Cu(II)

“…The thermal stability and decomposition of the complexes were studied in air using a Setsys 4 ] for which the magnetic susceptibility was assumed to be 1.644 9 10 -5 cm -3 g -1 . Correction for diamagnetism of the constituent atoms was calculated by the use of Pascal's constants [7].…”

“…These information may prove useful for assessing toxicity of pollutants in animal species [3]. 5-Chloro-2-nitrobenzoic acid was also used as component of synthesis of 2-aryl 4(3H)-quinazolinones [4] and 6-pyrrolidinyl-2-(2-substituted phenyl)-4-quinazolinones [5], which are potential anticancer candidates.…”

Synthesis and Photophysical Property Studies of the 2,6,8-Triaryl-4-(phenylethynyl)quinazolines

“…The potentially tautomeric quinazolin-4(3H)-one moiety itself is readily accessible via dehydrogenation of the corresponding 2,3-dihydroquinazolin-4(1H)-one precursors using oxidants such as KMnO 4 [10], CuCl 2 [11], DDQ [12] and MnO 2 [13] in stoichiometric or large access. The 2-substituted quinazolin-4(3H)-ones have also been synthesized directly from anthranilamide and aldehydes using NaHSO 3 [14], DDQ [15], CuCl 2 (3 equiv.) [16], FeCl 3 .6H 2 O [17] or I 2 [18].…”

Three-component one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives in 2,2,2-trifluoroethanol

“…Despite 2,3-dihydroquinazolinone usage in pharmaceutical and other industries, comparatively few methods for their preparation have been reported. In accordance with the significance of 2,3-dihydroquinazolinone, several synthetic methods have been developed for the construction of this kind of fused heterocycles from suitable precursors [30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45]. Very recently, Lee et al reported a one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones using ethylenediamine diacetate in aqueous media under reflux condition [46].…”