ChemInform Abstract: Synthesis of 3‐Fluoro‐2‐hetarylindoles and 3,3‐Difluoro‐2‐hetarylindolines Through Lewis Acid‐Catalyzed Formation of 3,3‐Difluoroindolium Ions.

Fong, Jacqueline Zi Mei; Choo, Simon Sze Shiong; Richard, Jean‐Alexandre; Garland, Marc; Guo, Liangfeng; Johannes, Charles W.; Nguyen, Tuan M.

doi:10.1002/chin.201525151

ChemInform

2015

DOI: 10.1002/chin.201525151

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ChemInform Abstract: Synthesis of 3‐Fluoro‐2‐hetarylindoles and 3,3‐Difluoro‐2‐hetarylindolines Through Lewis Acid‐Catalyzed Formation of 3,3‐Difluoroindolium Ions.

Jacqueline Zi Mei Fong¹,

Simon Sze Shiong Choo

Jean‐Alexandre Richard³

et al.

Abstract: The synthesis of various 3‐fluoro‐2‐hetarylindoles through addition of indoles, pyrroles, or alkyl‐substituted furans to 3,3‐difluoroindolium ions generated in situ by zinc triflate‐catalyzed oxazolidine ring opening is described.

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ChemInform Abstract: Synthesis of 3‐Fluoro‐2‐hetarylindoles and 3,3‐Difluoro‐2‐hetarylindolines Through Lewis Acid‐Catalyzed Formation of 3,3‐Difluoroindolium Ions.

Abstract: The synthesis of various 3‐fluoro‐2‐hetarylindoles through addition of indoles, pyrroles, or alkyl‐substituted furans to 3,3‐difluoroindolium ions generated in situ by zinc triflate‐catalyzed oxazolidine ring opening is described.

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References 1 publication

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