ChemInform Abstract: Synthesis and Reactions of 3‐Aminothiazolo(3,2‐a)benzimidazole‐2‐ carbonitrile.

Abstract

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Thiazolo[3,2-a]benzimidazoles: Synthetic Strategies, Chemical Transformations and Biological Activities

“…3-Aminothiazolo[3,2- a ]benzimidazol-2-carbonitrile ( 41 ) was prepared by the reaction of 2-mercabtobenzimidaziole ( 3) with bromomalononitrile ( 39 ) in ethanol followed by cyclization reaction of product 40 via anhydrous sodium acetate [ 11 , 47 , 48 ] ( Scheme 12 ).…”

“…Synthesis and reactions of 3-aminothiazolo[3,2- a ]bezimidazole-2-carbonitrile 41 were reported by Sarhan and his co-workers [ 11 , 47 , 48 , 86 , 87 , 88 , 89 ]. Condensation of compound 41 with aromatic aldehydes afforded the arylmethylidenes 170 .…”