“…Thiazole moiety is a ubiquitous scaffold and has involved in many natural and synthetic molecules having interesting activities such as antiviral, anticancer, antimicrobial, anticonvulsant, antiparkinson, and anti-inflammatory activities. − Similarly, coumarin moieties have involved in plants and have shown anticoagulation, antiviral, anti-inflammatory, antibacterial, and anticancer activities. Fused pyrimidines, chromenopyrimidine, and pyrimidines have also been reported as antiviral, antitumor, anti-inflammatory, antihypertensive activities, − calcium channel modulators, and antimicrobial agents. − Coumarins and their derivatives (Figure A) such as warfarin, coumatetralyl, and difenacoum are used as an anticoagulant, whereas phenprocoumon and bromadiolone have antiviral and potent rodenticide, respectively . Carbochromen is an effective coronary vasodilator.…”