ChemInform Abstract: Synthesis and Action on the Central Nervous System of 3‐Substituted 2‐ Phenyl‐2,3‐dihydro‐4H‐1,3,2‐benzoxazaphosphorin‐4‐one 2‐Oxide and 2‐ Sulfide Derivatives.

Abstract

1997 organo-phosphorus compounds, nonmetal heterocycles organo-phosphorus compounds, nonmetal heterocycles S 0087 -191Synthesis and Action on the Central Nervous System of 3-Substituted 2-Phenyl-2,3-dihydro-4H-1,3,2-benzoxazaphosphorin-4-one 2-Oxide and 2-Sulfide Derivatives.-The action of a series of earlier described benzoxazaphosphorinone 2-oxide (IV) and new 2-sulfide (III) derivatives on the central nervous system has been evaluated. The majority of these compounds exhibit neuroleptic activity. Moreover, sulfide derivatives act as antiserotoninergic drugs. -(KOSTKA, K.; PORADA, M.; ZYNER, E.; PAKULSKA, W.; SZADOWSKA, A.; Arch.