ChemInform Abstract: STRUCTURE OF COLEONOL, A BIOLOGICALLY ACTIVE DITERPENE FROM COLEUS FORSKOHLII

Parâmetros de qualidade físico-químicos e avaliação da atividade antioxidante de folhas de Plectranthus barbatus Andr. (Lamiaceae) submetidas a diferentes processos de secagem

“…(Lamiaceae) submetidas a diferentes processos de secagem de diversos diterpenos (Albuquerque et al, 2007;Bhat et al, 1977;Kelecom, 1984;Kelecom et al, 1987;Tandon et al, 1977;Wang et al, 1973;Zelnik et al, 1977), além de derivados fenólicos, tais como nepetoidinas A e B (Grayer et al, 2003) e o ácido rosmarínico (Falé et al, 2009). Estudos mais recentes têm reportado seu uso como um ingrediente de alimentos funcionais e suplementos alimentares para perda e controle de peso, tendo a forskolina como principal componente (Henderson et al, 2005;Kamohara & Noparatanawong, 2013;Kamohara et al, 2015).…”

Molecular and crystal structure of Forskolin

“…It is reported (Tandon et al, 1977) that it has the α-configuration in the 7-position. The cell constants are identical within the standard deviations.…”

“…It was possible to determine the relative configuration of the compound which is in contrast to that of Coleonol (Tandon et al, 1977). It was possible to determine the relative configuration of the compound which is in contrast to that of Coleonol (Tandon et al, 1977).…”

Molecular and crystal structure of Coleonol-B, C22H34O7

“…A number of diterpenoids isolated from the roots of the Indian plant Coleus forskohlii and designated as coleonols (Tandon, Dhar, Ramakumar, Venkatesan, 1977;Tandon, Jauhari, Singh, Dhar, 1978;Jauhari, Katti, Tandon, Dhar, 1978;Katti, Jauhari, Tandon, 1979) have shown interesting pharmacological effects. The stereostructure of the major constituent Coleonol was assigned by X-ray crystallography (Ramakumar, Venkatesan, Tandon, Dhar, 1985) and NMR spectroscopy (Prakash, Roy, Dhar, 1986).…”