ChemInform Abstract: Punarnavoside: A New Antifibrinolytic Agent from Boerhaavia diffusa Linn.

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

“…Although B. diffusa contains antifibrinolytic punarnavoside [9] , methanol extract of the plant showed significant (P<0.001) thrombolytic activity compared negative control. The phytochemical analysis showed that the BDME was a rich source of alkaloids, flavonoids, tannins and anthraquinones.…”

“…Pharmacological studies have demonstrated that B. diffusa known to possess anticonvulsant [4] , diuretic, anti-inflammatory, antifibrinolytic [9] , antibacterial [10] , anti-hepatotoxic, anthelmintic, febrifuge, anti-leprosy, antiasthmatic, antiurethritis, antilymphoproliferative [11] , antimetastatic [12] , immunosuppressive [13] , antidiabetic, antioxidant [14] , immune-modulation [15] , hepatoprotective [16] , anti-nociceptive, nephroprotective [17] , bacteria induced ulcer & diarrhea [18] and antiurolithiatic [19] activities. The identification of phytoconstituents and assay of antioxidant, thrombolytic, cytotoxic, antimicrobial activities were conducted using specific standard in vitro procedures.…”

Effect of chronic administration of <i>Boerhaavia diffusa</i> Linn. leaf extract on experimental diabetes in rats

“…The root and the whole plant are used as an Ayurvedic medicine in India and Unani medicine in Arab countries for the treatment of diabetes, stress, dyspepsia, abdominal pain, inflammation, jaundice, enlargement of spleen, congestive heart failure and bacterial infections [7][8][9][10][11] . The plant is known to possess anti-inflammatory [12][13] , anticonvulsant 14 , antifibrinolytic 15 , diuretic 16 , hepatoprotective [17][18][19][20] and immunomodulatory [21][22] activities. It has also been reported to be useful in the treatment of elephantiasis, night blindness, corneal ulcers and nephritic syndrome [23][24][25][26] .…”

In Vitro Antimicrobial Potential of Boerhavia Diffusa Leaf Extract on Pathogenic Organism

“…[4] B. diffusa leaf contains a large number of phytochemicals such as tannin, phytic acid, phenolics, saponins and trypsin which are considered as secondary metabolites and essential for their anti-oxidant activity. [29] Pharmacological studies have demonstrated that B. diffusa possesses diuretic action, [25] antiinflammatory, [3] antifibrinolytic, [14] anticonvulsant [21] and hepatoprotective activities. [5,23] B.…”

“…[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] It has also been reported to be useful in the treatment of elephantiasis, night blindness, corneal ulcers and nephritic syndrome. [20][21][22][23][24][25][26][27][28] www.wjpr.net Vol 6, Issue 05, 2017.…”