ChemInform Abstract: Preparation of 7‐Ethoxy‐3‐hydroxy‐6‐methoxy‐1‐methyl‐4‐ nitroisoquinoline.

Abstract

Preparation of 7-Ethoxy-3-hydroxy-6-methoxy-1-methyl-4-nitroisoquinoline.-A facile large-scale synthesis of the title isoquinoline (VII), which possesses both positive inotropic and systemic peripheral vasodilating activity, starting from commercially available phenylacetic acid (I) is given. -(BARTON, D. L.; FABIAN, A. C.; LAM, M. M.; STERBENZ, J. T.; J.