ChemInform Abstract: Phenanthrene Derivatives for Synthesis and Applications in Medicinal Chemistry: A Review

Azeredo, Oliveira Francisco de; Figueroa‐Villar, José Daniel

doi:10.1002/chin.201518320

Cited by 2 publications

(1 citation statement)

References 31 publications

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“…Phenanthrene serves as the fundamental nucleus in a number of opioid medicines and their derivatives, which are a potent class of analgesics from a pharmacological standpoint [7]. By examining trials on its derivatives, this study was conducted to highlight the many pharmacological applications of phenanthrene derivatives [8].…”

Section: Introductionmentioning

confidence: 99%

Isolation and Identification of Phenanthrene Degrading Bacteria from Polluted Soil in Iraq

2022

pnr

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Phenanthrene is a one of polycyclic aromatic hydrocarbon, it's considered slow decomposition pollutants in nature, and therefore they are treated in several ways and removed from the environment. The most important of these methods is biological treatment by microorganisms that are already present in the areas of presence of these pollutants. Soil samples were collected from oil-contaminated areas of Al-Dora and Sheikh Omar refinery area with a depth of (5-10) cm and a series of dilutions from (10-1) to (10-8) were made for them, then 0.1 ml was cultured on solid culture medium (nutrient agar). Twenty bacterial colonies were isolated and then cultured inside wells in Bushnell Haas Media agar that contain Phenanthrene as the sole source of carbon and energy. They were incubated at a temperature of 37°C for 7 days, then the growth zone was observed on two dishes. The two isolates grown on liquid Bushnell Haas Media were incubated in the shaker incubator at a temperature of 37°C and 150 rpm for 7 days. Then it was examined by HPLC High-performance liquid chromatography to know the percentage of bacteria degradation of Phenanthrene. After this, the most efficient bacterial isolates were diagnosed with the VITEK 2 device. Serratia ficaria and Bacillus subtilis showed the high degradation rates for Phenanthrene. Serratia ficaria degraded Phenanthrene by 91.36%, and Bacillus subtilis degradation was 91.72%.

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Section: Introductionmentioning

confidence: 99%

Isolation and Identification of Phenanthrene Degrading Bacteria from Polluted Soil in Iraq

2022

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Phenanthrene: A Versatile Molecule; A Review

Kwofie¹,

Gupta²

2021

PLANT ARCHIVES

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Phenanthrene is a nucleus of the poly aromatic hydrocarbon family consisting of three fused benzene rings. They are of great importance in the field of medicine. They are mainly synthesized through Bardhan-Sengupta synthesis, Haworth synthesis and Pschorr synthesis of phenanthrene. Presently, many naturally existing drugs such as morphine, codeine halofantrine, among others bear the phenanthrene nucleus. Synthetic derivatives including dextromethorphan and other drugs also possess this nucleus. Phenanthrene derivates have many distinct therapeutic benefits including analgesic, antitussive, antimalarial, cytotoxic, and anticonstipation. This study was performed to highlight the various pharmacological uses of phenanthrene derivatives by reviewing experiments performed on its derivatives.

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ChemInform Abstract: Phenanthrene Derivatives for Synthesis and Applications in Medicinal Chemistry: A Review

Abstract: Review: 38 refs.

Cited by 2 publications

References 31 publications

Isolation and Identification of Phenanthrene Degrading Bacteria from Polluted Soil in Iraq

Isolation and Identification of Phenanthrene Degrading Bacteria from Polluted Soil in Iraq

Phenanthrene: A Versatile Molecule; A Review

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