Phenanthrene is a nucleus of the poly aromatic hydrocarbon family consisting of three fused benzene rings. They are of great importance in the field of medicine. They are mainly synthesized through Bardhan-Sengupta synthesis, Haworth synthesis and Pschorr synthesis of phenanthrene. Presently, many naturally existing drugs such as morphine, codeine halofantrine, among others bear the phenanthrene nucleus. Synthetic derivatives including dextromethorphan and other drugs also possess this nucleus. Phenanthrene derivates have many distinct therapeutic benefits including analgesic, antitussive, antimalarial, cytotoxic, and anticonstipation. This study was performed to highlight the various pharmacological uses of phenanthrene derivatives by reviewing experiments performed on its derivatives.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.