Abstract:Heterocyclic Annulated Steroids from 2-Hydroxymethylene Canrenone.-A-ring annulated heterocycles, e.g. (II) or (V), are prepared starting from the title compound (I). Most of the synthesized compounds are inactive on the receptor level. (I) and (III) show weak binding affinity to the serum protein CBG. -(GOERLITZER, K.; MOORMANN, P.; POLLOW, K.; SCHAFFRATH, M.; Arch. Pharm. (Weinheim, Ger.) 328 (1995) 2, 157-160; Inst. Pharm. Chem., TU Braunschweig, D-38106 Braunschweig, Germany; DE)
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