ChemInform Abstract: Facile Synthesis of Bromoallenes via N‐Bromosuccinimide/CH<sub>3</sub>SCH<sub>3</sub> for the Bromination of Propargyl Alcohols.

Jiang, Wen Feng; Liu, Xue Song; Du, Xing; Ma, Jian wei; Bao, Chun Yu

doi:10.1002/chin.201302057

Cited by 1 publication

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“…904 Du et al reported a convenient pathway for the preparation of bromoallenes from propargyl alcohols by the combination of NBS and dimethyl sulfide. 905 Bromoallenes were obtained with high regioselectivity (Scheme 281). The substituents located at the para or meta position of the aromatic ring do not have a significant influence on the bromination, while the ortho position of the aromatic ring affects the bromination reaction, causing a lower yield of the product.…”

Section: Aromatic Bromination Using Nbsmentioning

confidence: 99%

Use of Bromine and Bromo-Organic Compounds in Organic Synthesis

2016

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Bromination is one of the most important transformations in organic synthesis and can be carried out using bromine and many other bromo compounds. Use of molecular bromine in organic synthesis is well-known. However, due to the hazardous nature of bromine, enormous growth has been witnessed in the past several decades for the development of solid bromine carriers. This review outlines the use of bromine and different bromo-organic compounds in organic synthesis. The applications of bromine, a total of 107 bromo-organic compounds, 11 other brominating agents, and a few natural bromine sources were incorporated. The scope of these reagents for various organic transformations such as bromination, cohalogenation, oxidation, cyclization, ring-opening reactions, substitution, rearrangement, hydrolysis, catalysis, etc. has been described briefly to highlight important aspects of the bromo-organic compounds in organic synthesis.

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Section: Aromatic Bromination Using Nbsmentioning

confidence: 99%