ChemInform Abstract: ELECTROPHILIC ACYLATION OF 1,2‐ AND 1,7‐DICARBAUNDECABORATES

Abstract

Das 1,2‐Dicarbanido‐undecaborat(‐1)kalium (I) reagiert mit Benzoylchlorid (II) zu einer orangeroten, im Vakuum destillierbaren Verbindung (III).

Polyhedral Boranes for Medical Applications: Current Status and Perspectives

“…It was first synthesized, as the racemic mixture, independently by Brattsev [36] and Zakharkin. [37] Subsequently, other methods of its synthesis in high yield, [38][39][40] as well as the stereoselective synthesis of the -isomer, [41] have been proposed.…”

A new approach to the synthesis of functional derivatives of nido-carborane: alkylation of [9-MeS-nido-7,8-C2B9H11]−

“…28 The synthetic utility of this approach is strongly limited by availability of the Grignard reagents containing respective functional groups. The direct acylation 29 and sulfenylation 30 of nido-carborane resulting in [9-RC(O)-7,8-C 2 B 9 H 11 ] − and [9-RS-7,8-C 2 B 9 H 11 ] − , respectively, look more promising; however, their synthetic utility is also limited by availability of acyl and sulfenyl chlorides containing various functional groups. Recently a new approach based on the introduction of a cyclic oxonium substituent (tetrahydrofuran or 1,4-dioxane) into the parent nido-carborane cage followed by the ring opening under nucleophilic attack was proposed for synthesis of nido-carborane derivatives with pendant functional groups.…”