ChemInform Abstract: Conversion of Some AM‐Butenolides and S‐Oxo‐2‐pyrrolines into Thiono Derivatives.

Abstract

Durch Behandlung der Butenolide (I) bzw. (IV) mit P2S5 (III) erhält man die Thioderivate (II) (orangefarben bis braun) bzw. (V) (rotbraun).

Non‐Aromatic 3H‐Pyrroles in the Reaction with Nucleophiles: Is High Reactivity a Myth?

“…For instance, hydration of different 3 H ‐pyrroles (Scheme a) by aqueous hydrochloric acid or on active surfaces (alumina and silica) was occasionally observed and even used for proof of their structure . Substitution of chlorine atom in 2‐chloro‐3 H ‐pyrroles under the action of pyrrolidine or potassium hydrosulfide was assumed to proceed in a stepwise manner through the addition of a nucleophile with further elimination of hydrogen chloride molecule (Scheme b). Also, the reversible addition of oxygen (methanol, ethanol) and nitrogen (dimethylamine, pyrrolidine, piperidine, morpholine) nucleophiles to the carbon–nitrogen double bond of 3 H ‐pyrroles with exo‐cyclic carbonyl function was reported (Scheme c) .…”