ChemInform Abstract: ANTIMYCOTIC AGENTS. XVII. HETEROCYCLICALLY SUBSTITUTED NITRILES

Abstract

Das aus Cyanamid (I) und symm.‐Triazin (II) gebildete Additionsprodukt (III) reagiert mit dem Piperidin (IV) bzw. dem Piperazin (VI) weiter zu den Cyanaminomethylenverbindungen (V) und (VII).

1H‐Benzimidazole‐2‐acetonitriles as synthon in fused benzimidazole synthesis

“…Cyanamide in the presence of methanol, s‐triazine and 3 gave primary product cyanoethene 141 which was stabilized via intermediate 142 to give pyridobenzimidazole 143 (Scheme ) [88].…”