ChemInform Abstract: ALKALOIDS OF VINCA ROSEA L. ISOLATION AND IDENTIFICATION OF CORONARIDINE

Abstract

We report on the isolation and the identification of the alkaloid coronari-The ' H NMR data are discussed. dine from Vinca rosea L.

Tertiary Indole Alkaloids of Tabernaemontana dichotoma Seeds

“…From spectral data (UV, IR, MS, 1H-NMR, '3C-NMR), the major alkaloid of the seeds was identified as stemmadenine (4) [5]. The other alkaloids were identified as coronaridine (1) [6], ibogamine (2) [7], tabersonine (5) [8], voacangine (3) [9], voaphylline (6) [10,11] by comparison of spectral data (UV, IR, MS, 'H-NMR) and Co-TLC with authentic samples.…”

“…IR (KBr disc) cm': 3400, 2950, 2850, 1700 (ester carbonyl), 1480, 1440, 1360, 1320, 720. MS (70 eV, 70° C) showed characteristic fragments at m/z (relative intensity %): 338 (M, 100), 323 (23), 309(5), 279(6), 253(8), 214 (22), 154 (20), 148(7), 136 (55), 130(10), 122 (21). 'H-NMR (300 MHz in CDCI3) ô in ppm: 7.81 (1H, bs, NH), 7.48 (1H, dd, H-12, j11 , = 7.5 Hz, j10 , = 1.5 Hz), 7.23 (1H, dd, H-9, J9 , = 7.5 Hz, J91, = 1.5 Hz), 7.15-7.08 (2H, dt, H-b, H-il, 9,o = = J1i.…”