ChemInform Abstract: A Novel Indigoid Antituberculosis Agent

Klein, Larry L.; Petukhova, Valentina; Wan, Baojie; Wang, Yuehong; Santasiero, Bernard D.; Lankin, David C.; Pauli, Guido F.; Franzblau, Scott G.

doi:10.1002/chin.201416143

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Molecules In Preclinical Study Phase1

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2015

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“…They are also easily manufactured and safe for human use. Substituted indigoids also perform via inhibition of protein kinase [89]. Nitrobenzothiazole and benzothiazoninethione derivatives possess antitubercular activity and are being tried in combination with other anti-TB drugs [90,91].…”

Section: Molecules In Preclinical Study Phasementioning

confidence: 99%

Newer Patents in Antimycobacterial Therapy

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2015

Pharm. Pat. Anal.

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Tuberculosis caused by Mycobacterium tuberculosis is a global health emergency. This deadly disease has far-reaching social and economic implications. Diseased individuals need prolonged polypharmacy which is not without ill effects. Treatment compliance is often compromised contributing to rising resistance. HIV co-infection has further worsened the scenario. On the other hand, no new anti-TB drug has hit the market in last 4-5 decades. After a long latency, only the last few years have witnessed growing research in this direction and a widening anti-TB drug clinical pipeline. The compounds in preclinical stage of development have also shown a heartening increase. The present review is an attempt to discuss novel promising patents in this field.

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Section: Molecules In Preclinical Study Phasementioning

confidence: 99%

Newer Patents in Antimycobacterial Therapy

Sk¹

2015

Pharm. Pat. Anal.

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ChemInform Abstract: A Novel Indigoid Antituberculosis Agent

Cited by 1 publication

References 1 publication

Newer Patents in Antimycobacterial Therapy

Newer Patents in Antimycobacterial Therapy

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