2016
DOI: 10.12973/ejac.2017.00154a
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Chemiluminescence System of Permanganate-Sulfite for Simple Determination of Zolpidem

Abstract: Zolpidem is an imidazopyridine agent for short term treatment of insomnia with a favorable adverse effect profile. A novel chemiluminescence (CL) method has been proposed for simple determination of zolpidem. The method is based on the fact that zolpidem can produce CL emission in the system of acidic KMnO4 (permanganate) and Na2SO3 (sulfite). On the optimized conditions of chemical variables, CL intensity was proportional to concentration of zolpidem in the range 2.5-295.1 ng mL-1. Limit of detection was 1.6 … Show more

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Cited by 3 publications
(2 citation statements)
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“…high performance liquid chromatography [6], GC/MS [7], chemiluminescence [8], spectrophotometry [9], radioimmunoassay [10], gas chromatography [11], and electrochemical methods [12,13].…”
Section: Original Research Articlementioning
confidence: 99%
“…high performance liquid chromatography [6], GC/MS [7], chemiluminescence [8], spectrophotometry [9], radioimmunoassay [10], gas chromatography [11], and electrochemical methods [12,13].…”
Section: Original Research Articlementioning
confidence: 99%
“…In recent years, numerous methods for detecting SO 3 2− have been reported, including titration, chromatography, capillary electrophoresis, electrochemistry, fluorimetry, and chemiluminescence. [7][8][9][10][11][12] And more and more researchers pay considerable attention to fluorimetry for its high sensitivity and selectivity, simple operation, non-invasiveness, real-time detection, and the desired spatiotemporal resolution. [13][14][15] In a word, fluorescent probes are being used as an effective molecular tool for the determination of various targets.…”
mentioning
confidence: 99%