Chemically modified electrodes. Molecular design for electroanalysis

Murray, Royce W.; Ewing, Andrew G.; Durst, Richard A.

doi:10.1021/ac00132a001

Cited by 217 publications

(128 citation statements)

References 51 publications

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“…Starting from bulky electrodes and beaker type electrochemical cells and going from mercury electrodes to interfaces based on bismuth and carbon much progress was made in electroanalysis in search of reproducible, inert electrodes, with less background current, and wide potential range [16,17,18]. These electrode materials were very promising in electro-analytical chemistry but lag behind in many features such as portability, low cost, low sample volume, and on-site analysis.…”

Section: Advantages Of Electrochemical Biosensors Based On Screen-mentioning

confidence: 99%

Electrochemical Affinity Biosensors Based on Disposable Screen-Printed Electrodes for Detection of Food Allergens

Vasilescu

Nunes

Hayat

et al. 2016

Sensors

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Food allergens are proteins from nuts and tree nuts, fish, shellfish, wheat, soy, eggs or milk which trigger severe adverse reactions in the human body, involving IgE-type antibodies. Sensitive detection of allergens in a large variety of food matrices has become increasingly important considering the emergence of functional foods and new food manufacturing technologies. For example, proteins such as casein from milk or lysozyme and ovalbumin from eggs are sometimes used as fining agents in the wine industry. Nonetheless, allergen detection in processed foods is a challenging endeavor, as allergen proteins are degraded during food processing steps involving heating or fermentation. Detection of food allergens was primarily achieved via Enzyme-Linked Immuno Assay (ELISA) or by chromatographic methods. With the advent of biosensors, electrochemical affinity-based biosensors such as those incorporating antibodies and aptamers as biorecognition elements were also reported in the literature. In this review paper, we highlight the success achieved in the design of electrochemical affinity biosensors based on disposable screen-printed electrodes towards detection of protein allergens. We will discuss the analytical figures of merit for various disposable screen-printed affinity sensors in relation to methodologies employed for immobilization of bioreceptors on transducer surface.

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Section: Advantages Of Electrochemical Biosensors Based On Screen-mentioning

confidence: 99%

Electrochemical Affinity Biosensors Based on Disposable Screen-Printed Electrodes for Detection of Food Allergens

Vasilescu

Nunes

Hayat

et al. 2016

Sensors

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“…Thus, either the physical properties of the electrode material are adapted for specific uses or functional groups are immobilized on the surface to improve the performance of the electrode. [1,27].…”

Section: Chemically Modified Electrodes (Cmes)mentioning

confidence: 99%

“…By controlling the potential, the electrode can be used as a variable free energy source (or sink) of electrons. In addition, electrons crossing the electrode-solution interface can be determined with great sensitivity by measuring current [1].…”

Section: Introductionmentioning

confidence: 99%

Chemically Modified Electrodes in Biosensing

Ciucu¹

2014

J Biosens Bioelectron

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The development of chemical sensors has received a great deal of scientific interest in the last decades. Not only the chemical industry may benefit from these sensors but also the food industry, bio-industry, medicine, environmental control because of their capability to give continuously and reversibly a selective and fast response to the presence of a specific compound in a complex mixture of components, without perturbing the system. Biosensors combine the power of analytical detection techniques with the specificity of biological recognition system and therefore they are the most promising devices today about this selectivity. Furthermore, biosensors possess many unique features such as compact size, simplicity of use, one-step reagentless analysis, absence of radioactivity, etc., that make them very attractive alternatives to conventional bioanalytical techniques. The present short review highlights some modern aspects of Chemically Modified Electrodes (CMEs) based on redox enzymes used in amperometric biosensing, a detection method which has already found a large number of applications in health care, food industry and environmental analysis. Some relevant applications of amperometric biosensors based on CMEs to real sample analysis are also presented and some possible future trends highlighted.

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“…By combining the intrinsic properties of the modifier and a given electrochemical reaction, CMEs exhibit significantly improved response compared to unmodified electrodes (Murray et al, 1987; Gilmartin and Hart, 1995; Cox et al, 1996). For heavy metals trace detection, the modification plays a critical role especially during the preconcentration step, by favoring selective and enhanced accumulation, thus leading to higher sensitivity and lower LODs (Arrigan, 1994).…”

Section: Introductionmentioning

confidence: 99%

Electrochemical sensors and devices for heavy metals assay in water: the French groups' contribution

et al. 2014

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A great challenge in the area of heavy metal trace detection is the development of electrochemical techniques and devices which are user-friendly, robust, selective, with low detection limits and allowing fast analyses. This review presents the major contribution of the French scientific academic community in the field of electrochemical sensors and electroanalytical methods within the last 20 years. From the well-known polarography to the up-to-date generation of functionalized interfaces, the different strategies dedicated to analytical performances improvement are exposed: stripping voltammetry, solid mercury-free electrode, ion selective sensor, carbon based materials, chemically modified electrodes, nano-structured surfaces. The paper particularly emphasizes their advantages and limits face to the last Water Frame Directive devoted to the Environmental Quality Standards for heavy metals. Recent trends on trace metal speciation as well as on automatic “on line” monitoring devices are also evoked.

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Chemically modified electrodes. Molecular design for electroanalysis

Cited by 217 publications

References 51 publications

Electrochemical Affinity Biosensors Based on Disposable Screen-Printed Electrodes for Detection of Food Allergens

Electrochemical Affinity Biosensors Based on Disposable Screen-Printed Electrodes for Detection of Food Allergens

Chemically Modified Electrodes in Biosensing

Electrochemical sensors and devices for heavy metals assay in water: the French groups' contribution

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