Chemical synthesis and antibacterial activity of novel-shaped silver nanoparticles

Abstract

Silver nanoparticles are useful for medical applications due to their strong antibacterial activity. The antibacterial activity can be tuned by controlling the size and shape of the prepared silver nanoparticles. In this work, silver nanoparticles with different sizes and shapes were synthesized by solution phase routes, and their interactions with Escherichia coli were studied. Triangular silver nanoprisms were prepared by the reduction of silver nitrate at room temperature in the presence of polyvinylpyrrolidone, sodium citrate, hydrogen peroxide and sodium borohydride. Spherical silver nanoparticles were also prepared using silver nitrate as metal precursor and sodium citrate as well as sodium borohydride as reducing agents. The morphologies and structures of the nanoparticles were characterized by transmission electron microscopy, UV-visible spectroscopy and X-ray diffraction. The results indicated that spherical silver nanoparticles were obtained with different average sizes of 4, 21 and 40 nm, respectively. The edged silver nanoprisms containing mainly {111} lattice planes were obtained in the range size of 25 to 400 nm. The antibacterial study revealed that the edged triangular silver nanoprisms with {111} lattice planes exhibited the strongest antibacterial property, compared with spherical nanoparticles. Our study demonstrated that triangular silver nanoprisms with sharp edges and sharp vertexes also display a good antibacterial activity in comparison to other shaped nanoparticles.

Comparative assessment of the apoptotic potential of silver nanoparticles synthesized by Bacillus tequilensis and Calocybe indica in MDA-MB-231 human breast cancer cells: targeting p53 for anticancer therapy

“…63 Dong et al reported that triangular nanoprisms with sharp edges and vertices possess very high antibacterial properties compared with spherical-shaped AgNPs. 70 Taken together, our results demonstrate that AgNPs undergo a shapedependent interaction with cancer cells.…”

Assessment of in situ-Prepared Polyvinylpyrrolidone-Silver Nanocomposite for Antimicrobial Applications

“…After that, the era of nanotechnology was * corresponding author; e-mail: hhasherif@yahoo.com emerged (1-100 nm) carrying highly promising properties of the silver for medical applications. At nanoscale, the ultra-small particle size brings about ultra-large surface area per mass therefore direct contact with ambiance is achieved by large number of atoms which are readily available for reaction [8,9]. AgNPs have specific properties such as high thermal conductivity and stability [10], and strong shape-dependent optical properties [11,12].…”

“…On the other hand, the synthesis of AgNPs by biosynthetic and biological methods through the interaction of plant extract, bacteria, fungi, actinomycetes and algae has been widely explored [26]. Although physical and biological approaches have been established to be an alternative to conventional methods, the chemical methods are still more versatile [9].…”

“…Fortunately, chemical reduction method is chosen to be applied due to its advantages of being rapid, simple and economical way to produce AgNPs with well-controlled size and shape, using reducing and stabilizing agents to prevent these nanoparticles from agglomeration [9]. A soluble silver salts (either in water or organic solvent) is reduced by any of the reducing agents as citrate, ethyl glycol, glucose, or sodium borohydride [27].…”

Improved Yield of Green Synthesized Crystalline Silver Nanoparticles With Potential Antioxidant Activity

“…Commercially, SNPs are synthesized by means of chemical methods using reducing agents such as sodium borohydride, hydrazine, N, N-dimethylformamide in the presence of stabilizers like triphenylphosphine, citrate, polyvinylpyrrolidone [3][4][5] . The prepared SNPs have a high surface area which leads to the adsorption of these potentially toxic chemicals.…”