Chemical structure of antitumor polysaccharide, coriolan, produced by Coriolus versicolor.

Miyazaki, Toshio; Yadomae, Toshiro; Sugiura, Masahiro; Ichikawa, Hitoshi; Fujii, Kiichiro; Naruse, Sensuke; Kunihisa, Masahiro

doi:10.1248/cpb.22.1739

Cited by 25 publications

(8 citation statements)

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“…Preparation of antitumor polysaccharide: The cultured mycelium of C. versicolor (4) was washed with distilled water, disintegrated in a mixer, and extracted with boiling water for 5 hr. The suspension was filtered to remove the insoluble materials.…”

Section: Methodsmentioning

confidence: 99%

Studies on antitumor polysaccharides, especially D-II, from mycelium of Coriolus versicolor.

et al. 1980

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Section: Methodsmentioning

confidence: 99%

Studies on antitumor polysaccharides, especially D-II, from mycelium of Coriolus versicolor.

et al. 1980

Self Cite

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“…These fungi are well known as a medicinal mushroom in traditional therapeutic practice in Japan, China, Korea and other Asian countries (Cui & Chisti 2003). Their polysaccharides have shown antitumour activity and include protein-bound polysaccharides extracted from the fungal mycelium like the Krestin (PSK) and Polysaccharopeptide (PSP) (Sugiura et al 1980;Ng 1998) and the extracellular polysaccharide Coriolan (Miyazaki et al 1974).…”

Section: Introductionmentioning

confidence: 99%

Selection and Optimization of Culture Medium for Exopolysaccharide Production by Coriolus (Trametes) Versicolor

Tavares

Agapito

Coelho³

et al. 2005

World J Microbiol Biotechnol

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Coriolus versicolor is a medicinal fungus producing exopolysaccharides (EPS). Five well-defined culture media were studied to select the medium that maximizes production of EPS by C. versicolor. Biomass, reducing sugars and EPS concentrations along with the rheological behaviour of the broth were followed during fermentations lasting 9 days. The yeast malt extract medium (YM) was shown to yield the highest production of EPS. Fermentation conditions with YM medium were further investigated to optimize EPS production by C. versicolor. An experimental design to do this was adopted, in which the effects of pH and initial substrate concentration were considered. The effects of initial glucose concentration (5, 15 and 25 g l )1 ) and pH (4.0, 5.5 and 7.0) were evaluated. The initial glucose concentration was found to be the most important factor in EPS production and also cell growth.

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“…The known bioactive compounds of these Cordyceps species include cordycepin (Kredich and Guarino, 1960), ophicordin (Klenow, 1963), a polysaccharide (Miyazaki et al, 1974) galactomannan (Kiho et al, 1990), and l-tryptophan (Zhang et al, 1991), have been widely studied. Previous studies reported that Cordyceps militaris enhanced maturation of murine bone marrowderived dendritic cells in vitro and the antinociceptive activities (Won and Park, 2005;Kim et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Cordyceps militaris induces the IL-18 expression via its promoter activation for IFN-γ production

Kim

Lee

Cho

et al. 2008

Journal of Ethnopharmacology

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Chemical structure of antitumor polysaccharide, coriolan, produced by Coriolus versicolor.

Cited by 25 publications

References 0 publications

Studies on antitumor polysaccharides, especially D-II, from mycelium of Coriolus versicolor.

Studies on antitumor polysaccharides, especially D-II, from mycelium of Coriolus versicolor.

Selection and Optimization of Culture Medium for Exopolysaccharide Production by Coriolus (Trametes) Versicolor

Cordyceps militaris induces the IL-18 expression via its promoter activation for IFN-γ production

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