Chemical profiling and antimicrobial activity of essential oil from Curcuma aeruginosa Roxb., Curcuma glans K. Larsen &amp; J. Mood and Curcuma cf. xanthorrhiza Roxb. collected in Thailand

Akarchariya, Nararat; Sirilun, Sasithorn; Julsrigival, Jakaphun; Chansakaowa, Sunee

doi:10.1016/j.apjtb.2017.09.009

Cited by 69 publications

(51 citation statements)

References 13 publications

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“…Maybe some of the metabolites in RCA, not only lavonoids, were obtained that had antioxidant and cytotoxic activities. The results are supported the previous study, which showed that the essential oils from the C. aeruginosa possessed cytotoxic activity against bacteria (Kamazeri et al, 2012) (Akarchariya et al, 2017). Another study demonstrated that the C. aeruginosa rhizome contained various metabolite such as sesquiterpenes and terpenoids (Suphrom et al, 2012) (Simoh and Zainal, 2015).…”

Section: Correlation All Of the Biological Activitysupporting

confidence: 87%

Optimization of extraction process for extract yields, total flavonoid content, radical scavenging activity and cytotoxicity of Curcuma aeruginosa RoxB. rhizome

Qomaliyah¹,

Artika²,

Nurcholis³

2019

ijrps

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The rhizome of Curcuma aeruginosa RoxB. (RCA) is used traditionally for several diseases. The flavonoid compounds contained in the RCA that responsible for biological activities. In this study, ethanol, water, and acetone had been used as solvent extraction of RCA and applied the simplex-centroid design to optimize the extraction process. The radical scavenging activity and total flavonoid content were investigated using in vitro assays, while cytotoxicity was evaluated by brine shrimp lethality test. ANOVA suggested a linear model for all responses. The ethanol: acetone extract had the highest extract yield with a value of 25.15%, and this result showed no significant with acetone extract at p < 0.05 (22.86%). The ethanol extracts confirmed the higher degree of total flavonoid content and cytotoxicity with a value of 17.97 mg QE/g and 140 μg/ml, respectively. The ethanol: water extract, ethanol extract, and water extract (IC50, 100-500 μg/ml) showed moderate radical scavenging activity compared with ascorbic acid (IC50, 7.19 μg/ml). Regarding the correlation analysis, the negative correlation was weakly observed between flavonoid content and IC50 of free radical scavenging activity, which indicates that the flavonoid in RCA contributes not significantly to the antioxidant activity. Introductory studies on the extraction process of the advanced flavonoid extracts exhibited a scavenging and cytotoxic effect of the ethanol extract on C. aeruginosa rhizome.

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Section: Correlation All Of the Biological Activitysupporting

confidence: 87%

Optimization of extraction process for extract yields, total flavonoid content, radical scavenging activity and cytotoxicity of Curcuma aeruginosa RoxB. rhizome

Qomaliyah¹,

Artika²,

Nurcholis³

2019

ijrps

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“…Helen et al 29) reported that xanthorrhizol (55, 64.38%) was determined to be a major compound, followed by 48 (1.93%), camphene (56, 8.27%), and α-curcumene (57, 41.40%). Jarikasem et al 30) reported that 28 (37.58%) and 33 (13.70%) were the highest proportion components found in this plant part. 31) Other compounds include monoterpen 42 (0.29%), isoborneol (58, 0.04%), camphor (59, 0.21%), E-elemene (60, 4.60%), and trans-caryophyllene (61, (63).…”

Section: Curcuma Xanthorrhizamentioning

confidence: 79%

Chemical Constituents and Bioactivities of Several Indonesian Plants Typically Used in Jamu

Widyowati

Agil

2018

CHEMICAL & PHARMACEUTICAL BULLETIN

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This article reviews the chemical constituents and bioactivities of several Indonesian plants typically used in Jamu prescriptions in Indonesia. Jamu is Indonesia traditional medicine: it consists of either a single ingredient or a mixture of several medicinal plants. One plant family always used in Jamu is Zingiberaceae (ginger), such as Curcuma domestica/C. longa, C. xanthorrhizae, C. heyneana, C. zedoaria, C. aeruginosa, Zingiber aromaticum, Alpinia galanga. We also report other commonly used plant families such as Justicia gendarussa and Cassia siamea, whose activities have been extensively explored by our department.

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“…Curcuma aeruginosa Roxb., namely temu ireng or temu hitam in Indonesia, is one of the most popular rhizomatous medicinal plant belonging to the family Zingiberaceae and genus Curcuma (Sasikumar 2005). The previous works had shown that the rhizome of C. aeruginosa has beneficial biological activities such as antioxidant (Nurcholis et al 2015a), antimicrobial (Kamazeri et al 2012;Akarchariya et al 2017), hair-growth and skin lightening (Srivilai et al 2017), anti-androgenic (Suphrom et al 2012), uterine relaxant (Thaina et al 2009), and anti-dengue (Moektiwardoyo et al 2014). In this context, C. aeruginosa is an important raw material for an industry of traditional medicine.…”

Section: Introductionmentioning

confidence: 99%

Phenolic and flavonoid content in ethanol extract and agro-morphological diversity of Curcuma aeruginosa accessions growing in West Java, Indonesia

et al. 2019

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Abstract. Khumaida N, Syukur M, Bintang M, Nurcholis W. 2019. Phenolic and flavonoid content in ethanol extract and agro-morphological diversity of Curcuma aeruginosa accessions growing in West Java, Indonesia. Biodiversitas 20: 656-663. Curcuma aeruginosa is a rhizomatous medicinal plant with beneficial pharmacological activities. The aim of this work was to analyze the agro-morphological, extract yield, and phenolic content of ten C. aeruginosa accessions which were collected from different locations in Indonesia. Cultivation was carried out in the open field in West Java of Indonesia using a completely randomized design. Qualitative and quantitative parameters were used to investigate agro-morphological traits. Total phenolic and total flavonoids contents were determined in ethanol extracts of samples. The plants were phenotypically diverse, in which there were significant variations among the ten C. aeruginosa accessions in number of leaves, plant height, number of shoots, fresh weight of rhizome, and dry weight of rhizome characters. Variability in the total phenolic and total flavonoid contents ranged from 29.08-46.92 mg GAE/g, and 21.31-33.81 mg QE/g, respectively. Six accessions had high phenolic content and extract yield. Therefore, these accessions could be utilized for commercial scale and also showed a high potency for medicinal plant breeding programs.

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Chemical profiling and antimicrobial activity of essential oil from Curcuma aeruginosa Roxb., Curcuma glans K. Larsen & J. Mood and Curcuma cf. xanthorrhiza Roxb. collected in Thailand

Cited by 69 publications

References 13 publications

Optimization of extraction process for extract yields, total flavonoid content, radical scavenging activity and cytotoxicity of Curcuma aeruginosa RoxB. rhizome

Optimization of extraction process for extract yields, total flavonoid content, radical scavenging activity and cytotoxicity of Curcuma aeruginosa RoxB. rhizome

Chemical Constituents and Bioactivities of Several Indonesian Plants Typically Used in Jamu

Phenolic and flavonoid content in ethanol extract and agro-morphological diversity of Curcuma aeruginosa accessions growing in West Java, Indonesia

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