Chemical Profile and Use of the Peat as an Adsorbent for Extraction of Volatile Compounds from Leaves of Geranium (Pelargonium graveolens L’ Herit)

Niculau, Edenilson dos Santos; Alves, Péricles Barreto; Nogueira, Paulo César de Lima; Romão, Luciane Pimenta Cruz; Cunha, Graziele da Costa; Blank, Arie Fitzgerald; Silva, Anderson de Carvalho

doi:10.3390/molecules25214923

Cited by 6 publications

(2 citation statements)

References 24 publications

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“…In the recovery of volatile terpenoids, differences have been observed in the type of compounds that are obtained when using steam distillation methods and those of adsorption. In the study carried out by Niculau et al (2020) on the extraction of volatile terpenoids from geranium, it was shown that there are differences in the profile of compounds recovered with hydrodistillation and two dynamic adsorption methods for the headspace. With hydrodistillation, no monoterpenes were recovered, only monoterpenoids, sesquiterpenes, and esters, of which the main ones are linalool and citronellyl formate, in a higher proportion compared to adsorption methods.…”

Section: Recovery Of Terpenes and Terpenoids With Steam Distillation ...mentioning

confidence: 99%

Factors that influence the extraction methods of terpenes from natural sources

González-Hernández,

Valdez-Cruz,

Trujillo-Roldán

2024

Chem. Pap.

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Due to their various applications, terpenes and terpenoids are secondary metabolites of industrial interest. These compounds can be found in a wide variety of organisms from virtually all biological kingdoms. However, it has been identified that various factors in the production process, such as the place and time of harvest, pretreatments, extraction, and purification, generate differences in the profile of terpenes and terpenoids that can be obtained from organisms. The first factor that influences the extraction of compounds is drying since an inappropriate choice of the drying method can lead to the loss of the compounds of interest or the appearance of others that arise due to the decomposition of the original molecules. Similarly, Soxhlet extraction is the most used method in the recovery of terpenoids due to its high extraction efficiency. However, unconventional extraction methods have proven to be effective alternatives for terpenoid recovery, particularly the use of microwave and high-pressure extraction, as well as the use of unconventional solvents, achieving extraction efficiencies equal to or greater than Soxhlet in shorter times. This review will address the differences observed in the extraction of terpenoids and the main factors that cause them, as well as a comparison of the advantages and disadvantages of the various methodologies for drying, extraction, and separation of these compounds.

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Section: Recovery Of Terpenes and Terpenoids With Steam Distillation ...mentioning

confidence: 99%

Factors that influence the extraction methods of terpenes from natural sources

González-Hernández,

Valdez-Cruz,

Trujillo-Roldán

2024

Chem. Pap.

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“…is an aromatic herb in the Geraniaceae family that is native to a few geographical areas of South Africa, and mainly distributed throughout the Mediterranean region [ 14 , 15 ]. Around the world, PGEO is widely utilized as a pharmaceutical, cosmetic, and flavoring agent as well as in folkloric foods and aromatherapy industries [ 14 , 16 , 17 ]. It is one of the best oils utilized in skincare due to its effectiveness in cleaning oily skin and opening pores.…”

Section: Introductionmentioning

confidence: 99%

Chemical Markers and Pharmacological Characters of Pelargonium graveolens Essential Oil from Palestine

et al. 2022

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Pelargonium graveolens leaves are widely used in traditional medicine for relieving some cardiovascular, dental, gastrointestinal, and respiratory disorders. They are also used as food and tea additives in Palestine and many other countries. Consequently, this investigation aimed to describe the chemical markers, cytotoxic, antioxidant, antimicrobial, metabolic, and cyclooxygenase (COX) enzymes inhibitory characteristics of P. graveolens essential oil (PGEO) from Palestine utilizing reference methods. There were 70 chemicals found in the GCMS analysis, and oxygenated terpenoids were the most abundant group of the total PGEO. Citronellol (24.44%), citronellyl formate (15.63%), γ-eudesmol (7.60%), and iso-menthone (7.66%) were the dominant chemical markers. The EO displayed strong antioxidant activity (IC50 = 3.88 ± 0.45 µg/mL) and weak lipase and α-amylase suppressant effects. Notably, the PGEO displayed high α-glucosidase inhibitory efficacy compared with Acarbose, with IC50 doses of 52.44 ± 0.29 and 37.15 ± 0.33 µg/mL, respectively. PGEO remarkably repressed the growth of methicillin-resistant Staphylococcus aureus (MRSA), even more than Ampicillin and Ciprofloxacin, and strongly inhibited Candida albicans compared with Fluconazole. The highest cytotoxic effect of the PGEO was noticed against MCF-7, followed by Hep3B and HeLa cancer cells, with IC50 doses of 32.71 ± 1.25, 40.71 ± 1.89, and 315.19 ± 20.5 µg/mL, respectively, compared with doxorubicin. Moreover, the screened EO demonstrated selective inhibitory activity against COX-1 (IC50 = 14.03 µg/mL). Additionally, PGEO showed a weak suppressant effect on COX-2 (IC50 = 275.97 µg/mL). The current research can be considered the most comprehensive investigation of the chemical and pharmacological characterization of the PGEO. The results obtained in this study demonstrate, without doubt, that this plant represents a rich source of bioactive substances that can be further investigated and authenticated for their medicinal potential.

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