Chemical–physical properties of TheraCal, a novel light‐curable MTA‐like material for pulp capping

Abstract

TheraCal displayed higher calcium-releasing ability and lower solubility than either ProRoot MTA or Dycal. The capability of TheraCal to be cured to a depth of 1.7 mm may avoid the risk of untimely dissolution. These properties offer major advantages in direct pulp-capping treatments.

Cytotoxicity and biocompatibility of resin-free and resin-modified direct pulp capping materials: A state-of-the-art review

“…After 6, 30, and 60 days of restorations with these materials, the levels of aluminium (Al) in the plasma in which MTA Angelus (322-529 ppb) and MTA Fillapex (299-468 ppb) were implanted, were around twice as high as Theracal LC (143-226 ppb) and the control (102-155 ppb) groups 39) . It is likely that TheraCal LC released less Al because of its lower solubility 31) and shorter setting time (immediately lightcured) which reduces the chance of Al-release prior to the setting of the material 39) .…”

“…Compared to conventional calcium silicates/ MTA materials, the resin-modified version has several advantages, including immediate light-polymerization, preventing wash out of material, and superior physical properties 30) . One study showed that TheraCal LC presented higher calcium release than MTA (ProRoot) and calcium hydroxide (Dycal) throughout a 28-day test period, while its solubility was significantly lower 31) . The pH profile of the medium conditioned by TheraCal LC was similar as that of ProRoot MTA (from 11 to 8) during the 28-day test 31) .…”

“…One study showed that TheraCal LC presented higher calcium release than MTA (ProRoot) and calcium hydroxide (Dycal) throughout a 28-day test period, while its solubility was significantly lower 31) . The pH profile of the medium conditioned by TheraCal LC was similar as that of ProRoot MTA (from 11 to 8) during the 28-day test 31) . Similar to other types of calcium hydroxides or calcium silicates materials (Dycal, Calcicur, Calcimol LC, MTA Angelus, and Biodentine), TheraCal LC exhibited valuable antibacterial activity 32) .…”

“…TheraCal LC contains a hydrophilic monomer/polymer matrix, while Calcimol LC, VLC Dycal, and Ultra-Blend Plus contain a hydrophobic monomer/polymer matrix. The hydrophilic matrix allows higher calcium and hydroxide release, which are very important in protecting pulp their ability to stimulate dentin formation and provide antibacterial action (high alkalinity), respectively 6,31,33) . Both TheraCal LC and resin-modified calcium hydroxide were shown to be more cytotoxic to murine odontoblasts cells and human dental pulp stem cells than resin-free calcium silicates, such as Biodentine, MTA Angelus, and ProRoot MTA, but they showed similar or lower cytotoxicity than Dycal (vitality with MTT test after 72 h: resin-modified materials: 14-15%, resin-free MTA 28-35%, Dycal 9%; number of vital cells with Alamar blue tests after 72 h: resin-modified materials: 33000-35000, resin-free MTA 333000-533000, Dycal 30000) 8,34) .…”

Farkli Astar Ve Kai̇de Materyalleri̇ni̇n Kompozi̇t Rezi̇ni̇n Makaslama Bağlanma Dayanimina Etki̇si̇

“…İçeriğindeki kalsiyum silikat, apatit kristallerinin oluşumunu indükle-mesinin yanı sıra daha düzenli dentin köprüsünün oluşumunu da sağlamaktadır. 13,28 Bu materyallerin kompozit rezine ve dentine olan bağlanma dayanımı ile ilgili çalışmalar çok azdır. Oskoee ve ark.…”