Chemical modification of an acidic polysaccharide (TAPA1) from Tremella aurantialba and potential biological activities

Du, Xiu-Ju; Zhang, Jingsong; Lv, Zhiwei; Ye, Libin; Yang, Yan; Tang, Qingjiu

doi:10.1016/j.foodchem.2013.07.137

Cited by 55 publications

(33 citation statements)

References 12 publications

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“…The estimated molecular weight of American ginseng immunostimulatory polysaccharide PPQA2 and PPQA4 reported in our study was within this range. Du et al [38] recently found that acetyl-polysaccharide (content higher acetyl groups) showed markedly increasing immunostimulation potency, while deac-polysaccharide (without acetyl groups) had weak effect compared with the primary one. Although the molecular weight of polysaccharide PPQA5 (5.3 × 10 3 Da) was less than 10,000 Da, the existence of acetyl groups might contribute to its inmmunostimulating activity.…”

Section: Discussionmentioning

confidence: 99%

Structural features and immunostimulating effects of three acidic polysaccharides isolated from Panax quinquefolius

Wang

Yao

Sang

et al. 2015

International Journal of Biological Macromolecules

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Section: Discussionmentioning

confidence: 99%

Structural features and immunostimulating effects of three acidic polysaccharides isolated from Panax quinquefolius

Wang

Yao

Sang

et al. 2015

International Journal of Biological Macromolecules

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“…The main mechanism is that the acetyl groups could make polysaccharide branches stretch and change orientation, causing the generation of polysaccharide molecules with transverse order. The alteration of spatial arrangement of polysaccharide chains can result in the exposure of polysaccharide hydroxyl groups, and thus increase solubility in water (Duand others ). This method has already been successfully applied to cellulose modification (Barud and others ).…”

Section: Major Methods Of Molecular Modification Of Polysaccharidesmentioning

confidence: 99%

“…Acetylated polysaccharides are able to donate more electrons and quickly terminate the radical chain reactions. The acetylated derivatives of pumpkin polysaccharide can exhibit higher protective effects than natural polysaccharide, in terms of inhibiting cell death induced by H 2 O 2 and cell apoptosis of rats’ thymic lymphocytes (Duand others ).…”

Section: Influence Of Molecular Modification On Bioactivities Of Polymentioning

confidence: 99%

Molecular Modification of Polysaccharides and Resulting Bioactivities

Xiong

Lai

et al. 2015

Comp Rev Food Sci Food Safe

398

172

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Polysaccharides are ideal natural resources for supplements and pharmaceuticals that have received more and more attention over the years. Natural polysaccharides have been shown to have fewer side effects, but because of their inherently physicochemical properties, their bioactivities were difficult to compare with those of synthetic drugs. Thus, researchers have modified the structures and properties of natural polysaccharides based on structure-activity relationships and have obtained better functionally improved polysaccharides. This review focuses on the major modification methods of polysaccharides, and discusses the effect of molecular modification on their physicochemical properties and bioactivities. Molecular modification methods mainly include chemical, physical, and biological changes. Chemical modification is the most widely used method; it can significantly increase the water solubility and bioactivities of polysaccharides by grafting onto other groups. Physical and biological modifications only change the molecular weight of a polysaccharide, and thereby change its physicochemical properties and bioactivities. Most of the molecular modifications bring about an increase in the antioxidant activity of polysaccharides, and among these, sulfated and acetylated modifications are very common. Furthermore, phosphorylation modification is the most common application to increase antitumor activity, and modified polysaccharides have been shown to have anti-HIV activity as the result of sulfated modification.

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“…It was conducted that the new absorption peak in the finer powders did not appear. Absorption peak at 1,726 cm −1 was attributed to the carbonyl (C=O) groups stretching vibration of polysaccharide structure from TAPs, which indicated that TAPs might be an acidic polysaccharide and/or contain O-acetyl groups (Du et al, 2014). In general, the bands at around 3,339 and 2,924 cm −1 were corresponding to -OH and C-H stretch vibration in polysaccharide structure of TAPs, respectively (Du et al, 2014).…”

Section: Ftir Analysis Of Tapsmentioning

confidence: 96%

“…The peaks at about 3,339, 2,921, 1,726, 1,642, 1,411, 1,237, 1,042, 797 and 593 cm −1 by FTIR spectra were clearly observed in Figure 3. In general, the bands at around 3,339 and 2,924 cm −1 were corresponding to -OH and C-H stretch vibration in polysaccharide structure of TAPs, respectively (Du et al, 2014). Table 5 presents the peak positions and assignments of the TAPs in detail.…”

Section: Ftir Analysis Of Tapsmentioning

confidence: 99%

Effect of pressure grinding technology on the physicochemical and antioxidant properties of Tremella aurantialba powder

Zhao

Liu

Zhang

et al. 2018

J Food Process Preserv

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Tremella aurantialba powders (TAPs) with different grinding time were prepared by pressure grinding technology. The physicochemical and antioxidant properties of TAPs were evaluated. The results showed that the bulk density, fluidity, surface number mean, and volume surface of TAPs decreased with the extending of grinding time, the surface area and polysaccharide contents significantly increased (p < 0.05). Grind time from 0 min to 25 min, the stickiness, bitterness, roughness, and mouthfell of TAPs were significant reductions except for increasing sweetness (p < 0.05). The finer TAPs showed the brighter color and higher DPPH and ·OH scavenging effects, while O2·- scavenging effect was not significantly different. FTIR analysis showed that the transformation of no major functional groups happened during superfine grinding. Practical applications The pressure grinding treatment will provide the basis of coursework for biomaterial powder engineering, and have great potential for being scaled‐up to a commercially processing of food materials from cost consideration. In addition, the development results in creating environmentally friendly processes.

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Chemical modification of an acidic polysaccharide (TAPA1) from Tremella aurantialba and potential biological activities

Cited by 55 publications

References 12 publications

Structural features and immunostimulating effects of three acidic polysaccharides isolated from Panax quinquefolius

Structural features and immunostimulating effects of three acidic polysaccharides isolated from Panax quinquefolius

Molecular Modification of Polysaccharides and Resulting Bioactivities

Effect of pressure grinding technology on the physicochemical and antioxidant properties of Tremella aurantialba powder

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