Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

Abdel‐Sattar, Essam; Abou-Hussein, Dina R.; Petereit, Frank

doi:10.4103/0974-8490.147136

Cited by 13 publications

(7 citation statements)

References 21 publications

(23 reference statements)

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“…When the present study is compared to ethnobotanical contributions done in KSA and neighboring countries, our findings disclosed that ten ethnobotanical uses of eight medicinal plants have been recorded for the first time [ Table 2 ]. [ 7 8 10 12 15 42 43 44 45 46 ] Little or no reports have been found so far regarding the bioactivity-guided fractionation of C. hirsute , J. procera , C. gileadensis , and D. foetida ; therefore, those plants can be a target for further bioactivity-guided isolation. Ethnobotanical use in particular of C. hirsute for managing vitiligo should be proved using melanocytes bioassay, vitiligo, a disease that affects about 0.5%–1% of the world's population that means about 60 million suffering from this disease.…”

Section: Discussionmentioning

confidence: 99%

“…In KSA, more than 1200 (over 50%) of the total flowering plants (2250) are expected to be of medicinal importance. [ 8 9 10 11 12 13 14 15 ] This indigenous knowledge and traditional experiences have been passed verbally devoid of documentation and the traditional healers are dying without passing their knowledge. Besides, the urbanization of the indigenous customs results in more and more loss of the old knowledge of this human heritage.…”

Section: Introductionmentioning

confidence: 99%

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Ethnopharmacological survey of medicinal plants in Albaha Region, Saudi Arabia

et al. 2017

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Background:Local natural medicinal resource knowledge is important to define and elaborate usage of herbs, in systematic and organized manner. Until recently, there has been little scientifically written document regarding the traditional uses of medicinal plants in Al Bahah region.Objective:This pilot study aims to collect the ethnobotanical information from native populations regarding the benefits of medicinal plants of Al Bahah region, and determine if the traditional usage is scientifically established (proved) from literature.Materials and Methods:The survey collected data for 39 plant species recorded by informants for their medicinal benefits. The recorded species were distributed among 28 plant families. Leguminosae and Euphorbiaceae were represented each by 3 species, followed by Asteraceae (2 species), Lamiaceae (2 species), Apocynaceae (2 species), and Solanaceae (2 species). All the medicinal plants were reported in their local names. Analysis of ethnopharmacological data was done to obtain percentage of plant families, species, parts of plants used, mode of administration, and preparation types.Results:Total 43 informants were interviewed, maximum number of species were used to cure skin diseases including burns (3), wounds (7), warts (1), Leishmania (7), topical hemostatic (2), followed by gastrointestinal system, rheumatism, respiratory tract problems, diabetes mellitus, anti-snake venom, malaria, and eye inflammation.Conclusions:The study covered Al Bahah city and its outskirts. Ten new ethnobotanical uses were recorded such as antirheumatic and anti-vitiligo uses for Clematis hirsute, leishmaniasis use of Commiphora gileadensis, antigout of Juniperus procera, removing warts for Ficus palmata.SUMMARY 39 plant species from 28 plant families are used for treating more than 20 types of diseases.Maximum number of species (23 species) was used for treating skin diseases (42.6%) including leishmaniasis, wound healing, dermatitis, psoriasis, vitiligo and warts.Ten ethnobotanical uses of 8 studied plants have not been previously reported.The most used medicinal plants, according to their Use Index (UI) were Juniperus procera, Rumex nervosus, and Ziziphus spina-christi. Abbreviations Used: UI : Use Index, GI: Gastrointestinal tract, RD: Rheumatic disease, CVS: Cardiovascular diseases, UTI: Urinary tract infection, DM: Diabetes mellitus, RT: Respiratory infection, KSA: Kingdom of Saudi Arabia

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Ethnopharmacological survey of medicinal plants in Albaha Region, Saudi Arabia

et al. 2017

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“…The flora of the Kingdom of Saudi Arabia (KSA) possesses approximately 1200 out of 2250 flowering plants that have medicinal importance [22]. Solanum incanum L. (family: Solanaceae) is one of the nightshade medicinal plants found in KSA and is endemic to sub-Saharan Africa, the Middle East, and India [23].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial and In Vitro Cytotoxic Efficacy of Biogenic Silver Nanoparticles (Ag-NPs) Fabricated by Callus Extract of Solanum incanum L.

et al. 2021

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The in vitro callus induction of Solanum incanum L. was executed on MS medium supplemented with different concentrations of auxin and cytokinin utilizing petioles and explants of leaves. The highest significant fresh weights from petioles and leaf explants were 4.68 and 5.13 g/jar for the medium supplemented with1.0 mg L−1 BA and 1.0 mg L−1 2,4-D. The callus extract of the leaves was used for the green synthesis of silver nanoparticles (Ag-NPs). Analytical methods used for Ag-NPs characterization were UV-vis spectroscopy, Fourier Transform Infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and Transmission Electron Microscopy (TEM). Spherical, crystallographic Ag-NPs with sizes ranging from 15 to 60nm were successfully formed. The FT-IR spectra exhibited the role of the metabolites involved in callus extract in reducing and capping Ag-NPs. The biological activities of Ag-NPs were dose-dependent. The MIC value for Staphylococcus aureus, Bacillus subtilis, and Escherichia coli was 12.5 µg mL−1, while it was 6.25 µg mL−1 for Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans. The highest inhibition of phytopathogenic fungi Alternaria alternata, Fusarium oxysporum, Aspergillus niger, and Pythium ultimum was 76.3 ± 3.7, 88.9 ± 4.1, 67.8 ± 2.1, and 76.4 ± 1.0%, respectively at 200 µg mL−1. Moreover, green synthesized Ag-NPs showed cytotoxic efficacy against cancerous cell lines HepG2, MCF-7 and normal Vero cell line with IC50 values of 21.76 ± 0.56, 50.19 ± 1.71, and 129.9 ± 0.94 µg mL−1, respectively.

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“…This, combined with its different habitats, contributes to a wide range of native and foreign medicinal plants. It is thought that more than 1200 of the 2250 flowering plants in Saudi Arabia can be used in traditional medicine ( Alqethami and Aldhebiani, 2021 , Abdel-Sattar et al, 2015 , Awadh Ali et al, 2017 , Amar and Lev, 2017 ). The medicinal plants used in the Kingdom of Saudi Arabia have been recorded in two volumes, “Medicinal Plants of Saudi Arabia,” published in 1987 and 2000 ( Mossa, 1987 , Alamgeer et al, 2013 , Alqethami et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Ethnomedicinal evaluation of medicinal plants used for therapies by men and women in rural and urban communities in Makkah district

Qari,

Alqethami,

Qumsani

2024

Saudi Pharmaceutical Journal

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Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

Cited by 13 publications

References 21 publications

Ethnopharmacological survey of medicinal plants in Albaha Region, Saudi Arabia

Ethnopharmacological survey of medicinal plants in Albaha Region, Saudi Arabia

Antimicrobial and In Vitro Cytotoxic Efficacy of Biogenic Silver Nanoparticles (Ag-NPs) Fabricated by Callus Extract of Solanum incanum L.

Ethnomedicinal evaluation of medicinal plants used for therapies by men and women in rural and urban communities in Makkah district

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